Research
Clinical trials
Every amyloidosis study now recruiting, about to open, or enrolling by invitation, anywhere in the world, listed straight from ClinicalTrials.gov and refreshed every day.
Information, not medical advice. The Alliance does not run these studies and cannot enrol you in one. If a trial looks relevant, discuss it with the doctor who follows your amyloidosis.
Recruiting and upcoming studies
The list covers AL, ATTR and AA amyloidosis as well as cerebral amyloid angiopathy. Each card says where the study stands: open to anyone who meets its criteria, not yet open, or restricted to people the investigators invite. Studies that close simply leave the list.
Showing 157–168 of 208 trials
RecruitingATTR (transthyretin)
US Benchmarking Clinical Study (opens on ClinicalTrials.gov)
The goal of this observational study is to measure shear wave velocity (SWV) in patients with non-reduced left ventricular ejection fraction (LVEF) heart failure…
- Study
- Observational (registry, imaging)
- Sponsor
- eMyosound SAS
Recruiting in: United States
NCT07215715Updated 20 October 2025
RecruitingNot specified
Hybrid Florbetaben PET/MRI for Imaging of Cardiac Amyloidosis (opens on ClinicalTrials.gov)
Exploration of prognostic parameters in 18F-Florbetaben PET/MRI in patients with cardiac amyloidosis. The clinical endpoints are defined as occurence of major adverse cardiac events…
- Study
- Observational (registry, imaging)
- Sponsor
- University Hospital, Essen
Recruiting in: Germany
NCT07154381Updated 4 September 2025
RecruitingAA (secondary)
Unclassified GENotypes of Autoinflammatory Diseases and AA Amyloidosis (opens on ClinicalTrials.gov)
Patients with autoinflammatory diseases (AID) have recurrent episodes of systemic inflammation accompanied by nonspecific elevation of blood inflammation markers typically absent between attacks. A…
- Study
- Observational (registry, imaging)
- Sponsor
- Assistance Publique – Hôpitaux de Paris
Recruiting in: France
NCT06354322Updated 2 September 2025
Not yet recruitingNot specified
Efficacy and Safety of Stapokibart for Primary Cutaneous Amyloidosis (opens on ClinicalTrials.gov)
This trial is planned to investigate the efficacy and safety of Stapokibart (an IL-4 receptor antagonist) in patients with PCA.
- Study
- Interventional (treatment)
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
No study locations listed yet
NCT07143864Updated 27 August 2025
RecruitingNot specified
Essen Amyloidosis Registry (opens on ClinicalTrials.gov)
The Essen Amyloidosis Registry (EAR) is a prospective, observational registry designed to collect comprehensive clinical data on patients diagnosed with systemic amyloidosis. The registry…
- Study
- Observational (registry, imaging)
- Sponsor
- University Hospital, Essen
Recruiting in: Germany
NCT06887283Updated 21 August 2025
Not yet recruitingATTR (transthyretin)
TEGSEDI Pregnancy Surveillance Program (opens on ClinicalTrials.gov)
This is a worldwide safety surveillance study of pregnancy outcomes in women with hATTR-PN who may have been exposed or were not exposed to…
- Study
- Observational (registry, imaging)
- Sponsor
- Akcea Therapeutics
No study locations listed yet
NCT04270058Updated 19 August 2025
RecruitingATTR (transthyretin)
Phenotyping and Characterization of wtATTR-CM (TRACE 1) (opens on ClinicalTrials.gov)
Descriptive cross-sectional study on 100 consecutive ATTRwt-CM patients reflecting all NAC stages aiming primarily to investigate ATTRwt-CM patient's quality of life (QoL) measures and…
- Study
- Observational (registry, imaging)
- Sponsor
- Steen Hvitfeldt Poulsen
Recruiting in: Denmark
NCT06291805Updated 15 August 2025
RecruitingNot specified
A Prospective Cohort Study on Primary Cutaneous Amyloidosis (opens on ClinicalTrials.gov)
The aim of this clinical trial is to find out whether the combination of tocilizumab tablets and acitretin capsules is more effective than acitretin…
- Study
- Interventional (treatment)
- Phase
- Phase 4
- Sponsor
- Army Medical University, China
Recruiting in: China
NCT06998875Updated 13 August 2025
RecruitingATTR (transthyretin)
To Evaluate the Efficacy and Safety of Tafamidis Meglumine Soft Capsules in the Treatment of Adult Patients With Transthyretin Amyloid Polyneuropathy (opens on ClinicalTrials.gov)
The purpose of this study is to evaluate the efficacy and safety of Tafamidis Meglumine Soft Capsules in the Treatment of Adult Patients with…
- Study
- Interventional (treatment)
- Phase
- Phase 4
- Sponsor
- Qilu Pharmaceutical Co., Ltd.
Recruiting in: China
NCT06940336Updated 30 July 2025
RecruitingAL (light chain)
Safety and Efficacy of Metabolically Armed BCMA CAR-T Cells (Meta10-BCMA) in the Treatment of r/r Plasma Cell Neoplasms Clinical Research (opens on ClinicalTrials.gov)
A Study of Metabolically Armed BCMA CAR-T Cells Therapy for Patients With Relapsed and/or Refractory Plasma Cell Neoplasms.
- Study
- Interventional (treatment)
- Phase
- Early phase 1
- Sponsor
- Anhui Provincial Hospital
Recruiting in: China
NCT07085559Updated 25 July 2025
RecruitingAL (light chain)
Teclistamab in Newly Diagnosed Mayo Stage IIIB AL Amyloidosis (opens on ClinicalTrials.gov)
This is a phase II study in patients with newly diagnosed Mayo stage IIIB immunoglobulin light-chain (AL) Amyloidosis to evaluate the efficacy and safety…
- Study
- Interventional (treatment)
- Phase
- Phase 2
- Sponsor
- Peking Union Medical College Hospital
Recruiting in: China
NCT07079423Updated 23 July 2025
RecruitingATTR (transthyretin)
Prevalence of Wild-type TTR Cardiac Amyloidosis in Patients With Polyneuropathy of Unknown Cause. (opens on ClinicalTrials.gov)
To investigate to what extent chronic axonal length-dependent polyneuropathy (CAP) and/or small-fiber neuropathy (SFN) is part of early non-cardiac manifestations of wild-type TTR cardiac…
- Study
- Interventional (treatment)
- Sponsor
- Universitair Ziekenhuis Brussel
Recruiting in: Belgium
NCT05950867Updated 22 July 2025
This list only covers amyloidosis studies that are open or about to open. The registry holds every study, including those already completed.
Source: ClinicalTrials.gov (U.S. National Library of Medicine). List last retrieved on 25 September 2026. clinicaltrials.gov
Not sure where to start?
Our member associations know the teams running these studies in their own country, and can help you prepare the conversation with your doctor.