Research

Clinical trials

Every amyloidosis study now recruiting, about to open, or enrolling by invitation, anywhere in the world, listed straight from ClinicalTrials.gov and refreshed every day.

Information, not medical advice. The Alliance does not run these studies and cannot enrol you in one. If a trial looks relevant, discuss it with the doctor who follows your amyloidosis.

Recruiting and upcoming studies

The list covers AL, ATTR and AA amyloidosis as well as cerebral amyloid angiopathy. Each card says where the study stands: open to anyone who meets its criteria, not yet open, or restricted to people the investigators invite. Studies that close simply leave the list.

Showing 193–204 of 208 trials

Not yet recruitingATTR (transthyretin)

Effect of Angiotensin Receptor/Neprilysin Inhibitors on Transthyretin Cardiac Amyloidosis and Heart Failure with Reduced Ejection Fraction (opens on ClinicalTrials.gov)

Prospective, randomized, multicenter, open-label clinical trial to evaluate the safety and efficacy of Sacubitril/Valsartan (Sac/Vals) compared to no initiation of the drug in patients…

Study
Interventional (treatment)
Phase
Phase 3
Sponsor
Puerta de Hierro University Hospital

Recruiting in: Spain

NCT06712030Updated 2 December 2024

RecruitingATTR (transthyretin)

Exploring Biomarkers in Hereditary Transthyretin Amyloidosis (opens on ClinicalTrials.gov)

Hereditary transthyretin amyloidosis (ATTRv, v for variant) is a severe and heterogeneous systemic condition due to mutations in the transthyretin (TTR) gene. The availability…

Study
Interventional (treatment)
Sponsor
Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Recruiting in: Italy

NCT05929209Updated 24 September 2024

RecruitingNot specified

A Multi-center Cardiac PYP Scan Registry in Taiwan (opens on ClinicalTrials.gov)

Amyloid deposition in the heart is called cardiac amyloidosis (CA); 95% is immunoglobulin light chain amyloidosis (AL) and transthyretin amyloidosis (ATTR). Hereditary (ATTRm) or…

Study
Observational (registry, imaging)
Sponsor
Far Eastern Memorial Hospital

Recruiting in: Taiwan

NCT05593679Updated 29 July 2024

RecruitingAL (light chain)

National Registry of Rare Kidney Diseases (opens on ClinicalTrials.gov)

The goal of this National Registry is to is to collect information from patients with rare kidney diseases, so that it that can be…

Study
Observational (registry, imaging)
Sponsor
UK Kidney Association

Recruiting in: United Kingdom

NCT06065852Updated 4 October 2023

RecruitingCerebral amyloid angiopathy

Prognosis of Cerebral Small Vessel Disease (opens on ClinicalTrials.gov)

Prognosis of small vessel disease (SVD) depends on the underlying type of SVD and index manifestation. The aim of this prospective, observational cohort study…

Study
Observational (registry, imaging)
Sponsor
Insel Gruppe AG, University Hospital Bern

Recruiting in: Switzerland

NCT05734378Updated 8 March 2023

This list only covers amyloidosis studies that are open or about to open. The registry holds every study, including those already completed.

Source: ClinicalTrials.gov (U.S. National Library of Medicine). List last retrieved on 25 September 2026. clinicaltrials.gov

Not sure where to start?

Our member associations know the teams running these studies in their own country, and can help you prepare the conversation with your doctor.