Research
Clinical trials
Every amyloidosis study now recruiting, about to open, or enrolling by invitation, anywhere in the world, listed straight from ClinicalTrials.gov and refreshed every day.
Information, not medical advice. The Alliance does not run these studies and cannot enrol you in one. If a trial looks relevant, discuss it with the doctor who follows your amyloidosis.

Recruiting and upcoming studies
The list covers AL, ATTR and AA amyloidosis as well as cerebral amyloid angiopathy. Each card says where the study stands: open to anyone who meets its criteria, not yet open, or restricted to people the investigators invite. Studies that close simply leave the list.
Showing 193–204 of 208 trials
Not yet recruitingNot specified
AI-enabled Screening and Diagnosis of Cardiomyopathies Using Coronary CTA (opens on ClinicalTrials.gov)
The goal of this observational and diagnostic study is to develop and validate an artificial intelligence assisted approach for coronary computer tomography angiography-(CCTA)-based screening…
- Study
- Observational (registry, imaging)
- Sponsor
- Shanghai Zhongshan Hospital
No study locations listed yet
NCT06748261Updated 27 December 2024
Not yet recruitingATTR (transthyretin)
Effect of Angiotensin Receptor/Neprilysin Inhibitors on Transthyretin Cardiac Amyloidosis and Heart Failure with Reduced Ejection Fraction (opens on ClinicalTrials.gov)
Prospective, randomized, multicenter, open-label clinical trial to evaluate the safety and efficacy of Sacubitril/Valsartan (Sac/Vals) compared to no initiation of the drug in patients…
- Study
- Interventional (treatment)
- Phase
- Phase 3
- Sponsor
- Puerta de Hierro University Hospital
Recruiting in: Spain
NCT06712030Updated 2 December 2024
RecruitingATTR (transthyretin)
Exploring Biomarkers in Hereditary Transthyretin Amyloidosis (opens on ClinicalTrials.gov)
Hereditary transthyretin amyloidosis (ATTRv, v for variant) is a severe and heterogeneous systemic condition due to mutations in the transthyretin (TTR) gene. The availability…
- Study
- Interventional (treatment)
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Recruiting in: Italy
NCT05929209Updated 24 September 2024
Not yet recruitingNot specified
Affection of Renal and Urinary System in IBD Patients (opens on ClinicalTrials.gov)
Detection and classification of different renal and urinary affection in patients with IBD that attended to Assist University Hospitals
- Study
- Observational (registry, imaging)
- Sponsor
- Assiut University
No study locations listed yet
NCT06249243Updated 30 July 2024
RecruitingNot specified
A Multi-center Cardiac PYP Scan Registry in Taiwan (opens on ClinicalTrials.gov)
Amyloid deposition in the heart is called cardiac amyloidosis (CA); 95% is immunoglobulin light chain amyloidosis (AL) and transthyretin amyloidosis (ATTR). Hereditary (ATTRm) or…
- Study
- Observational (registry, imaging)
- Sponsor
- Far Eastern Memorial Hospital
Recruiting in: Taiwan
NCT05593679Updated 29 July 2024
RecruitingAL (light chain)
Daratumumab for Patients With Light Chain Amyloidosis (opens on ClinicalTrials.gov)
This is a prospective, single-center study exploratory clinical trial, aim to exploring the efficacy and safety of daratumumab in patients with AL amyloidosis, patients…
- Study
- Interventional (treatment)
- Sponsor
- Nanjing University School of Medicine
Recruiting in: China
NCT06376214Updated 19 April 2024
Enrolling by invitationAL (light chain)
Autologous Stem Cell Transplantation for Patients With AL Amyloidosis (opens on ClinicalTrials.gov)
This study mainly evaluated the efficacy and safety of autologous stem cell transplantation for the treatment of AL amyloidosis, the role of induction and…
- Study
- Observational (registry, imaging)
- Sponsor
- Nanjing University School of Medicine
Recruiting in: China
NCT04210791Updated 26 February 2024
Not yet recruitingNot specified
Validation of Different Diagnostic Modalities in the Detection of Cardiac Amyloidosis Among Patients With “Red Flags” (opens on ClinicalTrials.gov)
The study aims to test and compare the diagnostic yield of different diagnostic modalities (speckle tracking echocardiography, CMR, serum and urine protein analysis and…
- Study
- Interventional (treatment)
- Sponsor
- Assiut University
No study locations listed yet
NCT06175858Updated 19 December 2023
RecruitingNot specified
DZHK TORCH-Plus is a Registry for Patients With Cardiomyopathies and Serves as Source for Cardiovascular Research Studies (opens on ClinicalTrials.gov)
The DZHK TranslatiOnal Registry for CardiomyopatHies (DZHK TORCH) represents a unique resource of clinical data and high quality biological samples to enable innovative clinical…
- Study
- Observational (registry, imaging)
- Sponsor
- University Hospital Heidelberg
Recruiting in: Germany
NCT04265040Updated 30 November 2023
RecruitingNot specified
Cardiac Amyloidosis Registry of University Hospital Leipzig (opens on ClinicalTrials.gov)
This is a clinical registry of patients with cardiac amyloidosis being treated at University Hospital Leipzig. The aim of the registry is to collect…
- Study
- Observational (registry, imaging)
- Sponsor
- University of Leipzig
Recruiting in: Germany
NCT06129656Updated 13 November 2023
RecruitingAL (light chain)
National Registry of Rare Kidney Diseases (opens on ClinicalTrials.gov)
The goal of this National Registry is to is to collect information from patients with rare kidney diseases, so that it that can be…
- Study
- Observational (registry, imaging)
- Sponsor
- UK Kidney Association
Recruiting in: United Kingdom
NCT06065852Updated 4 October 2023
RecruitingCerebral amyloid angiopathy
Prognosis of Cerebral Small Vessel Disease (opens on ClinicalTrials.gov)
Prognosis of small vessel disease (SVD) depends on the underlying type of SVD and index manifestation. The aim of this prospective, observational cohort study…
- Study
- Observational (registry, imaging)
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Recruiting in: Switzerland
NCT05734378Updated 8 March 2023
This list only covers amyloidosis studies that are open or about to open. The registry holds every study, including those already completed.
Source: ClinicalTrials.gov (U.S. National Library of Medicine). List last retrieved on 25 September 2026. clinicaltrials.gov
Not sure where to start?
Our member associations know the teams running these studies in their own country, and can help you prepare the conversation with your doctor.