AMYLOIDOSIS ALLIANCE The Voice of Patients

Research

Clinical trials

Every amyloidosis study now recruiting, about to open, or enrolling by invitation, anywhere in the world, listed straight from ClinicalTrials.gov and refreshed every day.

Information, not medical advice. The Alliance does not run these studies and cannot enrol you in one. If a trial looks relevant, discuss it with the doctor who follows your amyloidosis.

Recruiting and upcoming studies

The list covers AL, ATTR and AA amyloidosis as well as cerebral amyloid angiopathy. Each card says where the study stands: open to anyone who meets its criteria, not yet open, or restricted to people the investigators invite. Studies that close simply leave the list.

Showing 169–180 of 208 trials

RecruitingATTR (transthyretin)

Genistein in trAnSthyretin recePtor Amyloid caRdiomyopathy (opens on ClinicalTrials.gov)

This Phase 1b/2a study aims to investigate the safety and efficacy of genistein in patients with Transthyretin (TTR) Amyloidosis. The focus is on its…

Study
Interventional (treatment)
Phase
Phase 1
Sponsor
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Recruiting in: Canada

NCT06634108Updated 15 June 2025

RecruitingAL (light chain)

Teclistamab in Previously Treated AL Amyloidosis (opens on ClinicalTrials.gov)

This is a phase II study in patients with previously treated immunoglobulin light-chain (AL) Amyloidosis to evaluate the efficacy and safety of teclistamab

Study
Interventional (treatment)
Phase
Phase 2
Sponsor
Peking Union Medical College Hospital

Recruiting in: China

NCT06935162Updated 25 May 2025

Not yet recruitingNot specified

MCLENA-2: A Phase II Clinical Trial for the Assessment of Lenalidomide in Patients With Mild Cognitive Impairment (opens on ClinicalTrials.gov)

This is a randomized, double-blind, placebo-controlled, parallel group study. The use of placebo is appropriate to minimize bias related to treatment expectations of the…

Study
Interventional (treatment)
Phase
Phase 2
Sponsor
St. Joseph's Hospital and Medical Center, Phoenix

No study locations listed yet

NCT06177028Updated 18 May 2025

RecruitingATTR (transthyretin)

Thailand ATTR-CM Registry (opens on ClinicalTrials.gov)

The investigators of this registry aim to study the natural history, clinical presentation, characteristics, and imaging findings of patients diagnosed with ATTR amyloidosis in…

Study
Observational (registry, imaging)
Sponsor
Mahidol University

Recruiting in: Thailand

NCT06338696Updated 8 May 2025

RecruitingNot specified

Swiss Cardiac Amyloidosis REgistry (Swiss-CARE) (opens on ClinicalTrials.gov)

Cardiac transthyretin amyloidosis (ATTR), caused by ventricular depositions of misfolded transthyretin, results in an infiltrative cardiomyopathy, progressing from pronounced myocardial wall thickening, diastolic and…

Study
Observational (registry, imaging)
Sponsor
Insel Gruppe AG, University Hospital Bern

Recruiting in: Switzerland

NCT04776824Updated 6 May 2025

This list only covers amyloidosis studies that are open or about to open. The registry holds every study, including those already completed.

Search all studies on ClinicalTrials.gov (opens in a new tab)

Source: ClinicalTrials.gov (U.S. National Library of Medicine). List last retrieved on 25 September 2026. clinicaltrials.gov

Not sure where to start?

Our member associations know the teams running these studies in their own country, and can help you prepare the conversation with your doctor.

Find an association near you
Contact the Alliance