Research
Clinical trials
Every amyloidosis study now recruiting, about to open, or enrolling by invitation, anywhere in the world, listed straight from ClinicalTrials.gov and refreshed every day.
Information, not medical advice. The Alliance does not run these studies and cannot enrol you in one. If a trial looks relevant, discuss it with the doctor who follows your amyloidosis.
Recruiting and upcoming studies
The list covers AL, ATTR and AA amyloidosis as well as cerebral amyloid angiopathy. Each card says where the study stands: open to anyone who meets its criteria, not yet open, or restricted to people the investigators invite. Studies that close simply leave the list.
Showing 61–72 of 208 trials
RecruitingNot specified
Test-retest Study With [18F]FBB in Cardiac Amyloidosis (opens on ClinicalTrials.gov)
This study is an open-label study to evaluate and characterize test-retest reliability of [18F]florbetaben PET in subjects with AL-CA and ATTR-CA compared to non-CA…
- Study
- Interventional (treatment)
- Phase
- Phase 1
- Sponsor
- Lantheus Germany GmbH
Recruiting in: United Kingdom
NCT06790394Updated 3 August 2026
RecruitingNot specified
The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas (opens on ClinicalTrials.gov)
This phase II trial studies whether providing cancer treatment in the home is preferred over the traditional clinic setting and if it improves treatment…
- Study
- Interventional (treatment)
- Phase
- Phase 2
- Sponsor
- Mayo Clinic
Recruiting in: United States
NCT07285044Updated 30 July 2026
RecruitingATTR (transthyretin)
Cardiac Magnetic Resonance and Echocardiography Study With Acoramidis (opens on ClinicalTrials.gov)
The study aims to evaluate the effect of acoramidis on cardiac functional and structural improvement in participants with ATTR-CM.
- Study
- Interventional (treatment)
- Phase
- Phase 4
- Sponsor
- Eidos Therapeutics, a BridgeBio company
Recruiting in: United States
NCT07695701Updated 29 July 2026
Not yet recruitingNot specified
Detection of Cardiac Amyloidosis Using Right Ventricular Sensing Amplitude in Patients With Left Ventricular Hypertrophy (opens on ClinicalTrials.gov)
This multicenter prospective study aims to evaluate the diagnostic performance of right ventricular sensing amplitude measured during cardiac implantable electronic device (CIED) implantation (pacemaker…
- Study
- Interventional (treatment)
- Sponsor
- Assistance Publique – Hôpitaux de Paris
No study locations listed yet
NCT07734285Updated 29 July 2026
RecruitingAL (light chain)
Sonrotoclax Plus Dexamethasone With or Without Daratumumab Regimen in Patients With t(11;14) Primary AL Amyloidosis (opens on ClinicalTrials.gov)
The goal of this study is to evaluate the efficacy and safety of Sonrotoclax combined Regimen in patients with t(11;14) AL amyloidosis. Participants will…
- Study
- Interventional (treatment)
- Phase
- Phase 2
- Sponsor
- Peking University People's Hospital
Recruiting in: China
NCT07335887Updated 28 July 2026
RecruitingATTR (transthyretin)
A Phase 1 Study of 99mTc-p5+14 in Healthy Volunteers and Patients With AL or ATTR Systemic Amyloidosis (opens on ClinicalTrials.gov)
This study will investigate 99mTc-p5+14, an amyloid-reactive synthetic peptide, p5+14, radiolabeled with technetium-99m, as a radiotracer for detecting paamyloid deposits in patients with AL…
- Study
- Interventional (treatment)
- Phase
- Phase 1
- Sponsor
- University of Tennessee Graduate School of Medicine
Recruiting in: United States
NCT05951816Updated 24 July 2026
RecruitingAL (light chain)
BCMA/CD3 Bispecific Antibody Treatment for Newly Diagnosed Amyloidosis (opens on ClinicalTrials.gov)
This is a prospective, single-arm, single-center clinical study designed to evaluate the efficacy and safety of low-dose BCMA/CD3 bispecific antibody (CM336) in patients newly…
- Study
- Interventional (treatment)
- Phase
- Phase 2
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Recruiting in: China
NCT07151690Updated 23 July 2026
Not yet recruitingNot specified
Prospective Evaluation of Subcutaneous Administration of Daratumumab by the FreedomEDGE® Infusion System (opens on ClinicalTrials.gov)
This study is evaluating a new method for administering daratumumab, a treatment commonly used in the management of multiple myeloma and amyloidosis. For several…
- Study
- Interventional (treatment)
- Sponsor
- Hospices Civils de Lyon
Recruiting in: France
NCT07721350Updated 23 July 2026
RecruitingAL (light chain)
Study of GC012F, CAR-T Therapy Targeting CD19 and BCMA in Chinese Participants With Relapsed or Refractory AL Amyloidosis (opens on ClinicalTrials.gov)
This is a Phase 1b open-label, multicenter, non-randomized study of GC012F, a CD19/BCMA dual CAR T cell therapy, in adult participants with relapsed/refractory AL…
- Study
- Interventional (treatment)
- Phase
- Phase 1
- Sponsor
- Gracell Biotechnologies (Shanghai) Co., Ltd.
Recruiting in: China
NCT07250269Updated 23 July 2026
Enrolling by invitationNot specified
AI Echocardiographic Screening of Cardiac Amyloidosis (opens on ClinicalTrials.gov)
Recent advances in machine learning and image processing techniques have shown that machine learning models can identify features unrecognized by human experts and accurately…
- Study
- Interventional (treatment)
- Sponsor
- Cedars-Sinai Medical Center
Recruiting in: United States
NCT06664866Updated 22 July 2026
RecruitingNot specified
Artificial Intelligence Guided Echocardiographic Screening of Rare Diseases (EchoNet-Screening) (opens on ClinicalTrials.gov)
Despite rapidly advancing developments in targeted therapeutics and genetic sequencing, persistent limits in the accuracy and throughput of clinical phenotyping has led to a…
- Study
- Observational (registry, imaging)
- Sponsor
- Cedars-Sinai Medical Center
Recruiting in: United States
NCT05139797Updated 22 July 2026
RecruitingNot specified
[64Cu]FBP8 PET for Early Detection of Intracardiac Thrombus in Amyloid Cardiomyopathy (opens on ClinicalTrials.gov)
The primary goal of this pilot study is to determine whether [64Cu]FBP8, a novel fibrin-binding positron emission tomography (PET) probe, can identify intracardiac thrombi…
- Study
- Interventional (treatment)
- Phase
- Phase 3
- Sponsor
- Brigham and Women's Hospital
Recruiting in: United States
NCT07560306Updated 21 July 2026
This list only covers amyloidosis studies that are open or about to open. The registry holds every study, including those already completed.
Source: ClinicalTrials.gov (U.S. National Library of Medicine). List last retrieved on 25 September 2026. clinicaltrials.gov
Not sure where to start?
Our member associations know the teams running these studies in their own country, and can help you prepare the conversation with your doctor.