{"id":3407,"date":"2026-07-07T14:51:22","date_gmt":"2026-07-07T12:51:22","guid":{"rendered":"https:\/\/www.amyloidosisalliance.org\/typer-av-amyloidos\/"},"modified":"2026-11-02T17:31:42","modified_gmt":"2026-11-02T16:31:42","slug":"typer-av-amyloidos","status":"publish","type":"page","link":"https:\/\/www.amyloidosisalliance.org\/sv\/typer-av-amyloidos\/","title":{"rendered":"Typer av amyloidos"},"content":{"rendered":"\n<nav aria-label=\"Breadcrumb\" class=\"wp-block-group aa-breadcrumb is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"aa-inner\"><a href=\"\/\">Startsida<\/a><span class=\"aa-breadcrumb__sep\">\u203a<\/span><span class=\"aa-breadcrumb__label\">Amyloidos<\/span><span class=\"aa-breadcrumb__sep\">\u203a<\/span><span class=\"aa-breadcrumb__current\">Typer av amyloidos<\/span><\/div>\n<\/nav>\n\n<section class=\"wp-block-group aa-page-hero is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group aa-page-hero__grid is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group is-layout-flow wp-block-group-is-layout-flow\">\n<p class=\"aa-overline wp-block-paragraph\">Amyloidos<\/p>\n\n\n\n<h1 class=\"wp-block-heading\">Typer av amyloidos<\/h1>\n\n\n\n<p class=\"aa-lead wp-block-paragraph\">Amyloidos \u00e4r inte en enda sjukdom utan en familj av olika sjukdomar, som var och en definieras av vilket protein som felveckas och vilka organ som drabbas. Att f\u00f6rst\u00e5 varje typ \u00e4r f\u00f6rsta steget mot en korrekt diagnos och en riktad behandling.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group aa-page-hero__photo is-layout-flow wp-block-group-is-layout-flow\">\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1080\" height=\"1350\" src=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/Design-sans-titre.zip-6.jpg\" alt=\"\" class=\"wp-image-1190\" srcset=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/Design-sans-titre.zip-6.jpg 1080w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/Design-sans-titre.zip-6-240x300.jpg 240w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/Design-sans-titre.zip-6-819x1024.jpg 819w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/Design-sans-titre.zip-6-768x960.jpg 768w\" sizes=\"auto, (max-width: 1080px) 100vw, 1080px\" \/><\/figure>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n\n<nav aria-label=\"Section navigation\" class=\"wp-block-group aa-anchorband is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-columns aa-anchor-cols is-layout-flex wp-container-core-columns-is-layout-b2e659ba wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column aa-anchor-item is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"num wp-block-paragraph\">01<\/p>\n\n\n\n<p class=\"lbl wp-block-paragraph\"><a href=\"#diversity\">M\u00e5ngfalden<\/a><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column aa-anchor-item is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"num wp-block-paragraph\">02<\/p>\n\n\n\n<p class=\"lbl wp-block-paragraph\"><a href=\"#al\">AL-amyloidos<\/a><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column aa-anchor-item is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"num wp-block-paragraph\">03<\/p>\n\n\n\n<p class=\"lbl wp-block-paragraph\"><a href=\"#attr\">ATTR-amyloidos<\/a><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column aa-anchor-item is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"num wp-block-paragraph\">04<\/p>\n\n\n\n<p class=\"lbl wp-block-paragraph\"><a href=\"#aa\">AA-amyloidos<\/a><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column aa-anchor-item is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"num wp-block-paragraph\">05<\/p>\n\n\n\n<p class=\"lbl wp-block-paragraph\"><a href=\"#rarer\">Ovanligare typer<\/a><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column aa-anchor-item is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"num wp-block-paragraph\">06<\/p>\n\n\n\n<p class=\"lbl wp-block-paragraph\"><a href=\"#localized\">Lokaliserad<\/a><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column aa-anchor-item is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"num wp-block-paragraph\">07<\/p>\n\n\n\n<p class=\"lbl wp-block-paragraph\"><a href=\"#compare\">J\u00e4mf\u00f6r typerna<\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/nav>\n\n<section id=\"diversity\" class=\"wp-block-group aa-section aa-section--white aa-intro is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group is-layout-flow wp-block-group-is-layout-flow\">\n<p class=\"aa-section-num wp-block-paragraph\">01<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Amyloidosens stora m\u00e5ngfald<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Mer \u00e4n 40 m\u00e4nskliga prekursorproteiner \u00e4r k\u00e4nda f\u00f6r att bilda amyloidinlagringar. Amyloidos klassificeras efter vilket protein som bildar fibrillerna. De vanligaste systemiska formerna, AL, ATTR och AA, beror var och en p\u00e5 olika prekursorproteiner, drabbar olika organsystem och kr\u00e4ver helt olika behandlingsstrategier.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Eftersom symtomen ofta liknar dem vid vanligare sjukdomar \u00e4r en korrekt typning avg\u00f6rande, och den kr\u00e4ver specialiserade unders\u00f6kningar. En tidig och korrekt typning \u00e4r grunden f\u00f6r en effektiv v\u00e5rd.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group aa-intro__media is-layout-flow wp-block-group-is-layout-flow\">\n<figure class=\"aa-protein\" role=\"img\" aria-label=\"Illustration: ett korrekt veckat protein felveckas och staplas till amyloidfibriller\">\n\t\t\t\t<svg viewbox=\"0 0 480 360\" aria-hidden=\"true\" focusable=\"false\">\n\t\t\t\t\t<defs>\n\t\t\t\t\t\t<lineargradient id=\"aa-prot-core\" x1=\"0\" y1=\"0\" x2=\"1\" y2=\"1\">\n\t\t\t\t\t\t\t<stop offset=\"0%\" stop-color=\"#167a82\"><\/stop>\n\t\t\t\t\t\t\t<stop offset=\"100%\" stop-color=\"#00666d\"><\/stop>\n\t\t\t\t\t\t<\/lineargradient>\n\t\t\t\t\t\t<lineargradient id=\"aa-prot-fib\" x1=\"0\" y1=\"0\" x2=\"1\" y2=\"0\">\n\t\t\t\t\t\t\t<stop offset=\"0%\" stop-color=\"#f6a955\"><\/stop>\n\t\t\t\t\t\t\t<stop offset=\"100%\" stop-color=\"#f39325\"><\/stop>\n\t\t\t\t\t\t<\/lineargradient>\n\t\t\t\t\t<\/defs>\n\n\t\t\t\t\t<!-- Prot\u00e9ine correctement repli\u00e9e : h\u00e9lice compacte -->\n\t\t\t\t\t<g transform=\"translate(96 130)\">\n\t\t\t\t\t\t<circle r=\"62\" fill=\"#eaf3f3\"><\/circle>\n\t\t\t\t\t\t<path d=\"M-34 26 C-46 2 -26 -14 -6 -8 C14 -2 30 -16 22 -34\" fill=\"none\" stroke=\"url(#aa-prot-core)\" stroke-width=\"9\" stroke-linecap=\"round\"><\/path>\n\t\t\t\t\t\t<path d=\"M-26 40 C-4 44 18 30 26 10\" fill=\"none\" stroke=\"url(#aa-prot-core)\" stroke-width=\"9\" stroke-linecap=\"round\" opacity=\"0.55\"><\/path>\n\t\t\t\t\t\t<circle cx=\"22\" cy=\"-34\" r=\"7\" fill=\"#00666d\"><\/circle>\n\t\t\t\t\t\t<circle cx=\"-34\" cy=\"26\" r=\"7\" fill=\"#00666d\"><\/circle>\n\t\t\t\t\t<\/g>\n\n\t\t\t\t\t<!-- Transition -->\n\t\t\t\t\t<g stroke=\"#c9d2d6\" stroke-width=\"2\" stroke-linecap=\"round\">\n\t\t\t\t\t\t<line x1=\"176\" y1=\"130\" x2=\"212\" y2=\"130\" stroke-dasharray=\"2 8\"><\/line>\n\t\t\t\t\t\t<path d=\"M206 122 L216 130 L206 138\" fill=\"none\"><\/path>\n\t\t\t\t\t<\/g>\n\n\t\t\t\t\t<!-- Prot\u00e9ine mal repli\u00e9e : feuillets b\u00eata empil\u00e9s -->\n\t\t\t\t\t<g transform=\"translate(300 130)\">\n\t\t\t\t\t\t<g fill=\"none\" stroke=\"url(#aa-prot-fib)\" stroke-width=\"8\" stroke-linecap=\"round\">\n\t\t\t\t\t\t\t<path d=\"M-56 -34 L-20 -34 L-20 -14 L16 -14 L16 -34 L52 -34\"><\/path>\n\t\t\t\t\t\t\t<path d=\"M-56 -6 L-20 -6 L-20 14 L16 14 L16 -6 L52 -6\"><\/path>\n\t\t\t\t\t\t\t<path d=\"M-56 22 L-20 22 L-20 42 L16 42 L16 22 L52 22\"><\/path>\n\t\t\t\t\t\t<\/g>\n\t\t\t\t\t<\/g>\n\n\t\t\t\t\t<!-- Fibrille amylo\u00efde : les feuillets s'assemblent en filament -->\n\t\t\t\t\t<g transform=\"translate(240 268)\" fill=\"none\" stroke-linecap=\"round\">\n\t\t\t\t\t\t<path d=\"M-190 0 C-150 -22 -110 22 -70 0 C-30 -22 10 22 50 0 C90 -22 130 22 170 0\" stroke=\"url(#aa-prot-fib)\" stroke-width=\"7\"><\/path>\n\t\t\t\t\t\t<path d=\"M-190 14 C-150 -8 -110 36 -70 14 C-30 -8 10 36 50 14 C90 -8 130 36 170 14\" stroke=\"url(#aa-prot-fib)\" stroke-width=\"7\" opacity=\"0.45\"><\/path>\n\t\t\t\t\t<\/g>\n\n\t\t\t\t\t<text x=\"96\" y=\"222\" text-anchor=\"middle\" fill=\"#5a6a73\" font-family=\"'JetBrains Mono', ui-monospace, monospace\" font-size=\"12\" letter-spacing=\"1.4\">VECKAT<\/text>\n\t\t\t\t\t<text x=\"300\" y=\"222\" text-anchor=\"middle\" fill=\"#5a6a73\" font-family=\"'JetBrains Mono', ui-monospace, monospace\" font-size=\"12\" letter-spacing=\"1.4\">FELVECKAT<\/text>\n\t\t\t\t\t<text x=\"240\" y=\"320\" text-anchor=\"middle\" fill=\"#5a6a73\" font-family=\"'JetBrains Mono', ui-monospace, monospace\" font-size=\"12\" letter-spacing=\"1.4\">AMYLOIDFIBRILL<\/text>\n\t\t\t\t<\/svg>\n\t\t\t<\/figure>\n<\/div>\n<\/div>\n<\/section>\n\n<section id=\"al\" class=\"wp-block-group aa-section aa-section--cream aa-type is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group aa-type-split aa-type-split--photo-left is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group aa-type-photo is-layout-flow wp-block-group-is-layout-flow\">\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"\/wp-content\/themes\/amyloidosis-alliance\/assets\/images\/disease\/al-card.svg\" alt=\"\"\/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-group aa-type-text is-layout-flow wp-block-group-is-layout-flow\">\n<p class=\"aa-type-label wp-block-paragraph\">02 \u00b7 Systemisk<\/p>\n\n\n\n<h2 class=\"wp-block-heading aa-type-h\">AL-amyloidos<\/h2>\n\n\n\n<p class=\"aa-type-p wp-block-paragraph\">AL-amyloidos (l\u00e4tta kedjor) orsakas av en onormal tillv\u00e4xt av plasmaceller i benm\u00e4rgen som producerar felveckade l\u00e4tta kedjor av immunglobulin. Dessa fragment lagras in som amyloidfibriller, fr\u00e4mst i hj\u00e4rtat och njurarna, men kan drabba vilket organ som helst.<\/p>\n\n\n\n<p class=\"aa-type-p wp-block-paragraph\">Det \u00e4r den vanligaste formen av systemisk amyloidos i h\u00f6ginkomstl\u00e4nder. Behandlingen riktar sig mot den bakomliggande plasmacellssjukdomen, oftast med cytostatikabehandling liknande den som anv\u00e4nds vid multipelt myelom.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button aa-btn aa-btn--teal\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.amyloidosisalliance.org\/sv\/typer-av-amyloidos\/al-amyloidos\/\">Uppt\u00e4ck AL-amyloidos \u2192<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n\n<section id=\"attr\" class=\"wp-block-group aa-section aa-section--white aa-type is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group aa-type-split aa-type-split--photo-right is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group is-layout-flow wp-block-group-is-layout-flow\">\n<p class=\"aa-section-num wp-block-paragraph\">03 \u00b7 Systemisk<\/p>\n\n\n\n<h2 class=\"wp-block-heading aa-type-h\">ATTR-amyloidos<\/h2>\n\n\n\n<p class=\"aa-type-p wp-block-paragraph\">ATTR-amyloidos (transtyretin) uppst\u00e5r n\u00e4r transtyretin, ett protein som bildas i levern, blir instabilt och felveckas. Den drabbar fr\u00e4mst hj\u00e4rtat och det perifera nervsystemet och f\u00f6rekommer i tv\u00e5 olika former med olika orsaker och behandlingsv\u00e4gar.<\/p>\n\n\n\n<div class=\"wp-block-group aa-subtype-list is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group aa-subtype-row is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group is-layout-flow wp-block-group-is-layout-flow\">\n<p class=\"aa-subtype-row__name wp-block-paragraph\">ATTR av wild-type<\/p>\n\n\n\n<p class=\"aa-subtype-row__desc wp-block-paragraph\">Uppst\u00e5r spontant med stigande \u00e5lder och \u00e4r inte \u00e4rftlig. Visar sig oftast som kardiomyopati hos \u00e4ldre m\u00e4n. Uppt\u00e4cks allt oftare tack vare f\u00f6rb\u00e4ttrad bilddiagnostik av hj\u00e4rtat.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button aa-btn aa-btn--teal aa-btn--sm\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.amyloidosisalliance.org\/sv\/typer-av-amyloidos\/attrwt-amyloidos\/\">Uppt\u00e4ck \u2192<\/a><\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group aa-subtype-row is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group is-layout-flow wp-block-group-is-layout-flow\">\n<p class=\"aa-subtype-row__name wp-block-paragraph\">\u00c4rftlig ATTR<\/p>\n\n\n\n<p class=\"aa-subtype-row__desc wp-block-paragraph\">Orsakas av en mutation i TTR-genen. \u00c4rvs autosomalt dominant. Debut\u00e5lder och vilka organ som drabbas varierar med mutationen; neuropati \u00e4r ett typiskt k\u00e4nnetecken.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button aa-btn aa-btn--teal aa-btn--sm\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.amyloidosisalliance.org\/sv\/typer-av-amyloidos\/attrv-amyloidos\/\">Uppt\u00e4ck \u2192<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group aa-type-photo is-layout-flow wp-block-group-is-layout-flow\">\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"\/wp-content\/themes\/amyloidosis-alliance\/assets\/images\/disease\/attr-card.svg\" alt=\"\"\/><\/figure>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n\n<section id=\"aa\" class=\"wp-block-group aa-section aa-section--cream aa-type is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group aa-type-split aa-type-split--photo-left is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group aa-type-photo is-layout-flow wp-block-group-is-layout-flow\">\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"\/wp-content\/themes\/amyloidosis-alliance\/assets\/images\/disease\/aa-card.svg\" alt=\"\"\/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-group aa-type-text is-layout-flow wp-block-group-is-layout-flow\">\n<p class=\"aa-type-label wp-block-paragraph\">04 \u00b7 Systemisk<\/p>\n\n\n\n<h2 class=\"wp-block-heading aa-type-h\">AA-amyloidos<\/h2>\n\n\n\n<p class=\"aa-type-p wp-block-paragraph\">AA-amyloidos uppst\u00e5r som en sekund\u00e4r komplikation till en l\u00e5ngvarig systemisk inflammation. Det protein som orsakar sjukdomen, serumamyloid A (SAA), \u00e4r ett akutfasprotein som bildas i levern vid kroniska inflammatoriska tillst\u00e5nd som reumatoid artrit, inflammatorisk tarmsjukdom eller kroniska infektioner.<\/p>\n\n\n\n<p class=\"aa-type-p wp-block-paragraph\">Njurarna drabbas fr\u00e4mst, med proteinuri och tilltagande njursvikt som f\u00f6ljd. Behandlingen syftar till att kontrollera den bakomliggande inflammatoriska sjukdomen eller infektionen och att h\u00e4mma bildningen av serumamyloid A (SAA).<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button aa-btn aa-btn--teal\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.amyloidosisalliance.org\/sv\/typer-av-amyloidos\/aa-amyloidos\/\">Uppt\u00e4ck AA-amyloidos \u2192<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n\n<section id=\"rarer\" class=\"wp-block-group aa-section aa-section--white aa-type is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group aa-type-split aa-type-split--photo-right is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group is-layout-flow wp-block-group-is-layout-flow\">\n<p class=\"aa-section-num wp-block-paragraph\">05<\/p>\n\n\n\n<h2 class=\"wp-block-heading aa-type-h\">Ovanligare \u00e4rftliga typer<\/h2>\n\n\n\n<p class=\"aa-type-p wp-block-paragraph\">Ut\u00f6ver ATTR-amyloidos finns det andra genmutationer som orsakar ovanligare \u00e4rftliga former av systemisk amyloidos. Varje form definieras av sitt prekursorprotein och har sitt eget m\u00f6nster av organp\u00e5verkan. Gentestning \u00e4r n\u00f6dv\u00e4ndig f\u00f6r diagnosen och har betydelse f\u00f6r familjemedlemmarna.<\/p>\n\n\n\n<div class=\"wp-block-group aa-subtype-list is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group aa-rare-row is-layout-flow wp-block-group-is-layout-flow\">\n<p class=\"aa-rare-row__name wp-block-paragraph\">AAPOA1<\/p>\n\n\n\n<p class=\"aa-rare-row__desc wp-block-paragraph\">Mutation i apolipoprotein A-I. Drabbar njurarna, levern och de perifera nerverna. Autosomalt dominant ned\u00e4rvning.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button aa-btn aa-btn--teal aa-btn--sm\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.amyloidosisalliance.org\/sv\/typer-av-amyloidos\/sallsynta-arftliga-amyloidoser\/\">Uppt\u00e4ck \u2192<\/a><\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group aa-rare-row is-layout-flow wp-block-group-is-layout-flow\">\n<p class=\"aa-rare-row__name wp-block-paragraph\">AGEL<\/p>\n\n\n\n<p class=\"aa-rare-row__desc wp-block-paragraph\">Mutation i gelsolin. Ger fr\u00e4mst kranial neuropati och gitterdystrofi i hornhinnan. Vanligast i Finland.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button aa-btn aa-btn--teal aa-btn--sm\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.amyloidosisalliance.org\/sv\/typer-av-amyloidos\/sallsynta-arftliga-amyloidoser\/\">Uppt\u00e4ck \u2192<\/a><\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group aa-rare-row is-layout-flow wp-block-group-is-layout-flow\">\n<p class=\"aa-rare-row__name wp-block-paragraph\">ALYS<\/p>\n\n\n\n<p class=\"aa-rare-row__desc wp-block-paragraph\">Mutation i lysozym. Fr\u00e4mst njurp\u00e5verkan, med inlagringar i levern. Brittiska fall har historiskt beskrivits.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button aa-btn aa-btn--teal aa-btn--sm\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.amyloidosisalliance.org\/sv\/typer-av-amyloidos\/sallsynta-arftliga-amyloidoser\/\">Uppt\u00e4ck \u2192<\/a><\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group aa-rare-row is-layout-flow wp-block-group-is-layout-flow\">\n<p class=\"aa-rare-row__name wp-block-paragraph\">AFib<\/p>\n\n\n\n<p class=\"aa-rare-row__desc wp-block-paragraph\">Mutation i fibrinogenets alfakedja. Sjukdomen drabbar enbart njurarna; en av de vanligare \u00e4rftliga formerna i V\u00e4steuropa.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button aa-btn aa-btn--teal aa-btn--sm\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.amyloidosisalliance.org\/sv\/typer-av-amyloidos\/sallsynta-arftliga-amyloidoser\/\">Uppt\u00e4ck \u2192<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group aa-type-photo is-layout-flow wp-block-group-is-layout-flow\">\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"\/wp-content\/themes\/amyloidosis-alliance\/assets\/images\/disease\/rare-card.svg\" alt=\"\"\/><\/figure>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n\n<section id=\"localized\" class=\"wp-block-group aa-section aa-section--forest aa-type is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group aa-type-split aa-type-split--photo-left is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group aa-type-photo is-layout-flow wp-block-group-is-layout-flow\">\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"\/wp-content\/themes\/amyloidosis-alliance\/assets\/images\/disease\/localised-card.svg\" alt=\"\"\/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-group aa-type-text is-layout-flow wp-block-group-is-layout-flow\">\n<p class=\"aa-type-label wp-block-paragraph\">06 \u00b7 Lokaliserad<\/p>\n\n\n\n<h2 class=\"wp-block-heading aa-type-h\">Lokaliserad amyloidos<\/h2>\n\n\n\n<p class=\"aa-type-p wp-block-paragraph\">Till skillnad fr\u00e5n de systemiska formerna \u00e4r lokaliserad amyloidos begr\u00e4nsad till ett enda organ eller en enda v\u00e4vnad, oftast luftv\u00e4garna, huden, urinbl\u00e5san eller \u00f6gonh\u00e5lan. Amyloiden bildas lokalt av plasmaceller p\u00e5 plats och sprids inte i kroppen.<\/p>\n\n\n\n<p class=\"aa-type-p wp-block-paragraph\">Prognosen \u00e4r i regel b\u00e4ttre \u00e4n vid systemisk sjukdom, eftersom de vitala organens funktion s\u00e4llan p\u00e5verkas. Behandlingen beror p\u00e5 var sjukdomen sitter och hur omfattande den lokala v\u00e4vnadsskadan \u00e4r.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button aa-btn aa-btn--primary\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.amyloidosisalliance.org\/sv\/typer-av-amyloidos\/lokaliserad-amyloidos\/\">Uppt\u00e4ck \u2192<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n\n<section id=\"compare\" class=\"wp-block-group aa-section aa-section--cream aa-compare-sec is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group aa-centered-head is-layout-flow wp-block-group-is-layout-flow\">\n<p class=\"aa-section-num wp-block-paragraph\">07<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">J\u00e4mf\u00f6r typerna<\/h2>\n\n\n\n<div class=\"aa-divider-dot\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">En snabb\u00f6versikt \u00f6ver de viktigaste typerna av amyloidos: protein, fr\u00e4mst drabbade organ, behandlingsinriktning och var du kan l\u00e4sa mer.<\/p>\n<\/div>\n\n\n\n<figure class=\"wp-block-table aa-compare\"><table><thead><tr><th>Typ<\/th><th>Protein<\/th><th>Fr\u00e4mst drabbade organ<\/th><th>Behandlingsinriktning<\/th><th>L\u00e4s mer<\/th><\/tr><\/thead><tbody><tr><td>AL<\/td><td>L\u00e4tta kedjor av immunglobulin<\/td><td>Hj\u00e4rta, njurar, lever, nerver, mjukdelar<\/td><td>Cytostatikabehandling riktad mot plasmacellerna; stamcellstransplantation f\u00f6r patienter som bed\u00f6ms l\u00e4mpliga<\/td><td><a class=\"aa-compare__link\" href=\"https:\/\/www.amyloidosisalliance.org\/sv\/typer-av-amyloidos\/al-amyloidos\/\">AL-amyloidos \u2192<\/a><\/td><\/tr><tr><td>ATTR, wild-type<\/td><td>Transtyretin (wild-type)<\/td><td>Hj\u00e4rta (kardiomyopati)<\/td><td>Stabilisering av TTR och underst\u00f6djande hj\u00e4rtbehandling; godk\u00e4nda indikationer och tillg\u00e5ng varierar mellan l\u00e4nder.<\/td><td><a class=\"aa-compare__link\" href=\"https:\/\/www.amyloidosisalliance.org\/sv\/typer-av-amyloidos\/attrwt-amyloidos\/\">ATTRwt-amyloidos \u2192<\/a><\/td><\/tr><tr><td>ATTR, \u00e4rftlig<\/td><td>Transtyretin (muterat)<\/td><td>Perifera nerver, hj\u00e4rta (beroende p\u00e5 mutation)<\/td><td>TTR-h\u00e4mmare som tystar genen (siRNA, ASO); stabiliserare; levertransplantation (vissa mutationer)<\/td><td><a class=\"aa-compare__link\" href=\"https:\/\/www.amyloidosisalliance.org\/sv\/typer-av-amyloidos\/attrv-amyloidos\/\">ATTRv-amyloidos \u2192<\/a><\/td><\/tr><tr><td>AA<\/td><td>Serumamyloid A (SAA)<\/td><td>Njurar, lever, mj\u00e4lte<\/td><td>Kontroll av den bakomliggande inflammatoriska sjukdomen; IL-1-h\u00e4mmare<\/td><td><a class=\"aa-compare__link\" href=\"https:\/\/www.amyloidosisalliance.org\/sv\/typer-av-amyloidos\/aa-amyloidos\/\">AA-amyloidos \u2192<\/a><\/td><\/tr><tr><td>Ovanligare \u00e4rftliga<\/td><td>ApoA-I, gelsolin, lysozym, fibrinogen\u2026<\/td><td>Beroende p\u00e5 typ (njurar, nerver, lever)<\/td><td>Underst\u00f6djande behandling; organtransplantation i utvalda fall<\/td><td><a class=\"aa-compare__link\" href=\"https:\/\/www.amyloidosisalliance.org\/sv\/typer-av-amyloidos\/sallsynta-arftliga-amyloidoser\/\">S\u00e4llsynt \u00e4rftlig amyloidos \u2192<\/a><\/td><\/tr><\/tbody><\/table><\/figure>\n<\/div>\n<\/section>\n\n<section class=\"wp-block-group aa-next aa-next--split is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group aa-next__head is-layout-flow wp-block-group-is-layout-flow\">\n<p class=\"aa-section-num wp-block-paragraph\">Forts\u00e4tt<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">L\u00e4s vidare<\/h2>\n<\/div>\n\n\n\n<div class=\"wp-block-group aa-next__grid is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-group aa-next-card is-layout-flow wp-block-group-is-layout-flow\">\n<h3 class=\"wp-block-heading\"><a href=\"https:\/\/www.amyloidosisalliance.org\/sv\/typer-av-amyloidos\/al-amyloidos\/\">AL-amyloidos<\/a><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Den vanligaste systemiska formen i v\u00e4stv\u00e4rlden, orsakad av felveckade l\u00e4tta kedjor av immunglobulin.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group aa-next-card is-layout-flow wp-block-group-is-layout-flow\">\n<h3 class=\"wp-block-heading\"><a href=\"https:\/\/www.amyloidosisalliance.org\/sv\/typer-av-amyloidos\/attr-amyloidos\/\">ATTR-amyloidos<\/a><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">De tv\u00e5 formerna av transtyretinamyloidos, wild-type och \u00e4rftlig, och vad som skiljer dem \u00e5t.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group aa-next-card is-layout-flow wp-block-group-is-layout-flow\">\n<h3 class=\"wp-block-heading\"><a href=\"https:\/\/www.amyloidosisalliance.org\/sv\/typer-av-amyloidos\/sallsynta-arftliga-amyloidoser\/\">S\u00e4llsynta \u00e4rftliga amyloidoser<\/a><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">De ovanligare \u00e4rftliga formerna, de proteiner som \u00e4r inblandade och de organ som de oftast drabbar.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n","protected":false},"excerpt":{"rendered":"<p>Startsida\u203aAmyloidos\u203aTyper av amyloidos Amyloidos Typer av amyloidos Amyloidos \u00e4r inte en enda sjukdom utan en familj av olika sjukdomar, som var och en definieras av vilket protein som felveckas och vilka organ som drabbas. Att f\u00f6rst\u00e5 varje typ \u00e4r f\u00f6rsta steget mot en korrekt diagnos och en riktad behandling. 01 M\u00e5ngfalden 02 AL-amyloidos 03 ATTR-amyloidos [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-3407","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Typer av amyloidos: AL, AA, ATTR och s\u00e4llsynta former<\/title>\n<meta name=\"description\" content=\"Amyloidos \u00e4r inte en sjukdom utan en familj av sjukdomar. 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