{"id":3115,"date":"2026-07-10T14:54:26","date_gmt":"2026-07-10T12:54:26","guid":{"rendered":"https:\/\/www.amyloidosisalliance.org\/amiloidose-aa\/"},"modified":"2026-11-02T17:00:49","modified_gmt":"2026-11-02T16:00:49","slug":"amiloidose-aa","status":"publish","type":"page","link":"https:\/\/www.amyloidosisalliance.org\/pt\/tipos-de-amiloidose\/amiloidose-aa\/","title":{"rendered":"Amiloidose AA"},"content":{"rendered":"\n<nav class=\"wp-block-group aa-breadcrumb aa-events-hero__crumb is-layout-flow wp-block-group-is-layout-flow\" aria-label=\"Breadcrumb\">\n\t\n\t<div class=\"aa-inner\"><a href=\"\/\">In\u00edcio<\/a><span class=\"aa-breadcrumb__sep\">\u203a<\/span><span class=\"aa-breadcrumb__label\">Amiloidose<\/span><span class=\"aa-breadcrumb__sep\">\u203a<\/span><a href=\"https:\/\/www.amyloidosisalliance.org\/pt\/tipos-de-amiloidose\/\">Tipos de amiloidose<\/a><span class=\"aa-breadcrumb__sep\">\u203a<\/span><span class=\"aa-breadcrumb__current\">Amiloidose AA<\/span><\/div>\n\t\n<\/nav>\n\n<section class=\"wp-block-group aa-events-hero aa-events-hero--art aa-events-hero--aa is-layout-flow wp-block-group-is-layout-flow\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t<p class=\"aa-events-hero__kicker wp-block-paragraph\">Tipos de amiloidose<\/p>\n\t\t<h1 class=\"wp-block-heading\">Amiloidose AA<\/h1>\n\t\t<p class=\"wp-block-paragraph\">A amiloidose AA \u00e9 uma complica\u00e7\u00e3o de uma inflama\u00e7\u00e3o de longa dura\u00e7\u00e3o. N\u00e3o \u00e9 heredit\u00e1ria nem \u00e9 um cancro do sangue: desenvolve-se quando outra doen\u00e7a mant\u00e9m o organismo inflamado durante anos. \u00c9 ao controlar essa doen\u00e7a que se trava, o que faz da amiloidose AA a \u00fanica forma de amiloidose que pode realmente ser prevenida.<\/p>\n\t<\/div>\n\t\n\t\n\t<div class=\"wp-block-group aa-events-hero__art is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"\/wp-content\/themes\/amyloidosis-alliance\/assets\/images\/disease\/aa.svg\" alt=\"Esquema: uma inflama&#xE7;&#xE3;o cr&#xF3;nica produz uma prote&#xED;na que se dobra mal, se alinha e se empilha numa fibrilha amiloide\"\/><\/figure>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<nav class=\"wp-block-group aa-anchorband is-layout-flow wp-block-group-is-layout-flow\" aria-label=\"Section navigation\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-columns aa-anchor-cols is-layout-flex wp-container-core-columns-is-layout-b2e659ba wp-block-columns-is-layout-flex\">\n\t\t\t<div class=\"wp-block-column aa-anchor-item is-layout-flow wp-block-column-is-layout-flow\"><p class=\"num wp-block-paragraph\">01<\/p><p class=\"lbl wp-block-paragraph\"><a href=\"#what\">O que \u00e9 a AA?<\/a><\/p><\/div>\n\t\t\t<div class=\"wp-block-column aa-anchor-item is-layout-flow wp-block-column-is-layout-flow\"><p class=\"num wp-block-paragraph\">02<\/p><p class=\"lbl wp-block-paragraph\"><a href=\"#causes\">Como se desenvolve<\/a><\/p><\/div>\n\t\t\t<div class=\"wp-block-column aa-anchor-item is-layout-flow wp-block-column-is-layout-flow\"><p class=\"num wp-block-paragraph\">03<\/p><p class=\"lbl wp-block-paragraph\"><a href=\"#conditions\">Causas subjacentes<\/a><\/p><\/div>\n\t\t\t<div class=\"wp-block-column aa-anchor-item is-layout-flow wp-block-column-is-layout-flow\"><p class=\"num wp-block-paragraph\">04<\/p><p class=\"lbl wp-block-paragraph\"><a href=\"#symptoms\">Sintomas<\/a><\/p><\/div>\n\t\t\t<div class=\"wp-block-column aa-anchor-item is-layout-flow wp-block-column-is-layout-flow\"><p class=\"num wp-block-paragraph\">05<\/p><p class=\"lbl wp-block-paragraph\"><a href=\"#diagnosis\">Diagn\u00f3stico<\/a><\/p><\/div>\n\t\t\t<div class=\"wp-block-column aa-anchor-item is-layout-flow wp-block-column-is-layout-flow\"><p class=\"num wp-block-paragraph\">06<\/p><p class=\"lbl wp-block-paragraph\"><a href=\"#treatment\">Tratamento<\/a><\/p><\/div>\n\t\t\t<div class=\"wp-block-column aa-anchor-item is-layout-flow wp-block-column-is-layout-flow\"><p class=\"num wp-block-paragraph\">07<\/p><p class=\"lbl wp-block-paragraph\"><a href=\"#follow-up\">Preven\u00e7\u00e3o<\/a><\/p><\/div>\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/nav>\n\n<section class=\"wp-block-group aa-section aa-section--white aa-what is-layout-flow wp-block-group-is-layout-flow\" id=\"what\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">01<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">O que \u00e9 a amiloidose AA?<\/h2>\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-key-idea is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<p class=\"aa-key-idea__label wp-block-paragraph\">A reter<\/p>\n\t\t\t\t<p class=\"wp-block-paragraph\">A amiloidose AA \u00e9 uma complica\u00e7\u00e3o rara de uma inflama\u00e7\u00e3o persistente, causada na maioria das vezes por uma doen\u00e7a inflamat\u00f3ria ou infecciosa cr\u00f3nica. Encontrar a inflama\u00e7\u00e3o e trat\u00e1-la \u00e9 travar a subst\u00e2ncia amiloide na origem.<\/p>\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-what-cols is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-what-col is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<h4 class=\"wp-block-heading\">Uma prote\u00edna da inflama\u00e7\u00e3o<\/h4>\n\t\t\t\t<p class=\"wp-block-paragraph\">A subst\u00e2ncia amiloide da amiloidose AA \u00e9 formada pela <strong>prote\u00edna amiloide A s\u00e9rica<\/strong> (SAA), uma prote\u00edna produzida pelo f\u00edgado. Est\u00e1 normalmente presente no sangue em baixa concentra\u00e7\u00e3o, e a sua produ\u00e7\u00e3o aumenta acentuadamente sempre que o organismo entra em estado inflamat\u00f3rio.<\/p>\n\t\t\t\t<p class=\"wp-block-paragraph\">Esta resposta \u00e9 perfeitamente normal, e inofensiva, desde que seja breve. O problema come\u00e7a quando a inflama\u00e7\u00e3o dura anos em vez de semanas. A SAA circula ent\u00e3o em excesso, dobra-se mal e empilha-se em fibrilhas amiloides insol\u00faveis.<\/p>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-what-col is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<h4 class=\"wp-block-heading\">Os \u00f3rg\u00e3os que atinge<\/h4>\n\t\t\t\t<p class=\"wp-block-paragraph\">Os <strong>rins<\/strong>, antes de mais: s\u00e3o afetados na grande maioria dos doentes, e \u00e9 geralmente um problema renal que conduz ao diagn\u00f3stico.<\/p>\n\t\t\t\t<p class=\"wp-block-paragraph\">Os dep\u00f3sitos atingem tamb\u00e9m o tubo digestivo (est\u00f4mago e intestinos), bem como o f\u00edgado e as gl\u00e2ndulas salivares. Qualquer doen\u00e7a capaz de manter o organismo inflamado a longo prazo pode, em princ\u00edpio, conduzir a uma amiloidose AA.<\/p>\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<section class=\"wp-block-group aa-section aa-section--cream aa-forms is-layout-flow wp-block-group-is-layout-flow\" id=\"causes\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group aa-centered-head is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">02<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">Como se desenvolve a amiloidose AA<\/h2>\n\t\t\t<div class=\"aa-divider-dot\"><\/div>\n\t\t\t<p class=\"wp-block-paragraph\">Quatro etapas que transformam uma resposta imunit\u00e1ria comum numa doen\u00e7a dos \u00f3rg\u00e3os.<\/p>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-proc-grid is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<div class=\"wp-block-group aa-proc-step is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-proc-step__icon\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M8.5 14.5A2.5 2.5 0 0 0 11 12c0-1.38-.5-2-1-3-1.07-2.14-.22-4.05 2-6 .5 2.5 2 4.9 4 6.5 2 1.6 3 3.5 3 5.5a7 7 0 1 1-14 0c0-1.15.43-2.29 1-3a2.5 2.5 0 0 0 2.5 2.5z\"><\/path><\/svg><\/span><p class=\"aa-proc-step__num wp-block-paragraph\">Etapa 01<\/p><h4 class=\"wp-block-heading\">Inflama\u00e7\u00e3o cr\u00f3nica<\/h4><p class=\"wp-block-paragraph\">Outra doen\u00e7a mant\u00e9m o organismo inflamado: uma infe\u00e7\u00e3o prolongada, uma artrite inflamat\u00f3ria, uma doen\u00e7a intestinal, uma s\u00edndrome autoinflamat\u00f3ria.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-proc-step is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-proc-step__icon\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><polyline points=\"22 7 13.5 15.5 8.5 10.5 2 17\"><\/polyline><polyline points=\"16 7 22 7 22 13\"><\/polyline><\/svg><\/span><p class=\"aa-proc-step__num wp-block-paragraph\">Etapa 02<\/p><h4 class=\"wp-block-heading\">O f\u00edgado produz SAA<\/h4><p class=\"wp-block-paragraph\">Em resposta, o f\u00edgado aumenta a sua produ\u00e7\u00e3o de prote\u00edna amiloide A s\u00e9rica. Os n\u00edveis no sangue mant\u00eam-se elevados, n\u00e3o durante dias, mas durante anos a fio.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-proc-step is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-proc-step__icon\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><polyline points=\"16 3 21 3 21 8\"><\/polyline><line x1=\"4\" y1=\"20\" x2=\"21\" y2=\"3\"><\/line><polyline points=\"21 16 21 21 16 21\"><\/polyline><line x1=\"15\" y1=\"15\" x2=\"21\" y2=\"21\"><\/line><line x1=\"4\" y1=\"4\" x2=\"9\" y2=\"9\"><\/line><\/svg><\/span><p class=\"aa-proc-step__num wp-block-paragraph\">Etapa 03<\/p><h4 class=\"wp-block-heading\">Formam-se fibrilhas<\/h4><p class=\"wp-block-paragraph\">Ao circular em excesso, a SAA dobra-se mal e empilha-se em fibrilhas amiloides insol\u00faveis que o organismo n\u00e3o consegue eliminar.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-proc-step is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-proc-step__icon\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M10.29 3.86L1.82 18a2 2 0 0 0 1.71 3h16.94a2 2 0 0 0 1.71-3L13.71 3.86a2 2 0 0 0-3.42 0z\"><\/path><line x1=\"12\" y1=\"9\" x2=\"12\" y2=\"13\"><\/line><line x1=\"12\" y1=\"17\" x2=\"12.01\" y2=\"17\"><\/line><\/svg><\/span><p class=\"aa-proc-step__num wp-block-paragraph\">Etapa 04<\/p><h4 class=\"wp-block-heading\">Dep\u00f3sitos nos \u00f3rg\u00e3os<\/h4><p class=\"wp-block-paragraph\">As fibrilhas depositam-se nos tecidos, em primeiro lugar nos rins, e prejudicam progressivamente o seu funcionamento.<\/p><\/div>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-alert aa-tp-alert--wide is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"wp-block-paragraph\">Na amiloidose AA, a inflama\u00e7\u00e3o est\u00e1 geralmente presente h\u00e1 v\u00e1rios anos antes de a subst\u00e2ncia amiloide come\u00e7ar a formar-se.<\/p>\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<section class=\"wp-block-group aa-section aa-section--white aa-treating is-layout-flow wp-block-group-is-layout-flow\" id=\"conditions\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group aa-centered-head is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">03<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">O que mant\u00e9m a inflama\u00e7\u00e3o<\/h2>\n\t\t\t<div class=\"aa-divider-dot\"><\/div>\n\t\t\t<p class=\"wp-block-paragraph\">A amiloidose AA nunca surge sozinha. \u00c9 consequ\u00eancia de outra doen\u00e7a, e identificar qual \u00e9 o primeiro passo do tratamento.<\/p>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-treating-grid is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<div class=\"wp-block-group aa-treating-card is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-icon-tile\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M17 10c.7-.7 1.69 0 2.5 0a2.5 2.5 0 1 0 0-5 .5.5 0 0 1-.5-.5 2.5 2.5 0 1 0-5 0c0 .81.7 1.8 0 2.5l-7 7c-.7.7-1.69 0-2.5 0a2.5 2.5 0 0 0 0 5c.28 0 .5.22.5.5a2.5 2.5 0 1 0 5 0c0-.81-.7-1.8 0-2.5Z\"><\/path><\/svg><\/span><h3 class=\"wp-block-heading\">Artrites inflamat\u00f3rias<\/h3><p class=\"wp-block-paragraph\">As doen\u00e7as articulares que mant\u00eam o sistema imunit\u00e1rio ativo durante d\u00e9cadas est\u00e3o entre as causas mais frequentes.<\/p><ul class=\"wp-block-list aa-acc__tags\"><li>Artrite reumatoide<\/li><li>Artrite psori\u00e1tica<\/li><li>Espondilartrite<\/li><li>Gota<\/li><\/ul><\/div>\n\t\t\t<div class=\"wp-block-group aa-treating-card is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-icon-tile\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M2 15c6.667-6 13.333 0 20-6\"><\/path><path d=\"M2 9c6.667 6 13.333 0 20 6\"><\/path><line x1=\"7\" y1=\"6\" x2=\"9\" y2=\"8\"><\/line><line x1=\"15\" y1=\"16\" x2=\"17\" y2=\"18\"><\/line><\/svg><\/span><h3 class=\"wp-block-heading\">Doen\u00e7as autoinflamat\u00f3rias<\/h3><p class=\"wp-block-paragraph\">Doen\u00e7as gen\u00e9ticas que provocam surtos inflamat\u00f3rios repetidos, muitas vezes desde a inf\u00e2ncia. S\u00e3o os doentes para quem o rastreio \u00e9 mais importante.<\/p><ul class=\"wp-block-list aa-acc__tags\"><li>Febre mediterr\u00e2nica familiar<\/li><li>CAPS<\/li><li>MKD<\/li><li>TRAPS<\/li><\/ul><\/div>\n\t\t\t<div class=\"wp-block-group aa-treating-card is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-icon-tile\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M4 3v10a4 4 0 0 0 8 0V7a3 3 0 0 1 6 0v8\"><\/path><circle cx=\"18\" cy=\"18\" r=\"3\"><\/circle><\/svg><\/span><h3 class=\"wp-block-heading\">Doen\u00e7a inflamat\u00f3ria intestinal<\/h3><p class=\"wp-block-paragraph\">Uma inflama\u00e7\u00e3o prolongada do tubo digestivo, quando est\u00e1 mal controlada durante muitos anos.<\/p><ul class=\"wp-block-list aa-acc__tags\"><li>Doen\u00e7a de Crohn<\/li><li>Colite ulcerosa<\/li><\/ul><\/div>\n\t\t\t<div class=\"wp-block-group aa-treating-card is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-icon-tile\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M12 20c-3.3 0-6-2.7-6-6v-3a6 6 0 0 1 12 0v3c0 3.3-2.7 6-6 6z\"><\/path><path d=\"M12 20v-9\"><\/path><path d=\"M6 13H2\"><\/path><path d=\"M22 13h-4\"><\/path><path d=\"m8 2 1.9 1.9\"><\/path><path d=\"M16 2l-1.9 1.9\"><\/path><\/svg><\/span><h3 class=\"wp-block-heading\">Infe\u00e7\u00f5es cr\u00f3nicas<\/h3><p class=\"wp-block-paragraph\">Infe\u00e7\u00f5es que persistem em vez de se curarem, em particular as dos pulm\u00f5es.<\/p><ul class=\"wp-block-list aa-acc__tags\"><li>Infe\u00e7\u00f5es pulmonares<\/li><\/ul><\/div>\n\t\t\t<div class=\"wp-block-group aa-treating-card is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-icon-tile\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M12 22a7 7 0 0 0 7-7c0-2-1-3.9-3-5.5s-3.5-4-4-6.5c-.5 2.5-2 4.9-4 6.5S5 13 5 15a7 7 0 0 0 7 7z\"><\/path><\/svg><\/span><h3 class=\"wp-block-heading\">Doen\u00e7as do sangue<\/h3><p class=\"wp-block-paragraph\">Algumas doen\u00e7as hematol\u00f3gicas mant\u00eam um estado inflamat\u00f3rio a longo prazo.<\/p><ul class=\"wp-block-list aa-acc__tags\"><li>Mieloma<\/li><li>Linfoma n\u00e3o Hodgkin<\/li><li>Doen\u00e7a de Castleman<\/li><\/ul><\/div>\n\t\t\t<div class=\"wp-block-group aa-treating-card is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-icon-tile\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M12 3l2.5 6.5L21 12l-6.5 2.5L12 21l-2.5-6.5L3 12l6.5-2.5z\"><\/path><\/svg><\/span><h3 class=\"wp-block-heading\">Tumores s\u00f3lidos<\/h3><p class=\"wp-block-paragraph\">Uma causa mais rara, mas reconhecida. Alguns tumores mant\u00eam uma inflama\u00e7\u00e3o cr\u00f3nica.<\/p><ul class=\"wp-block-list aa-acc__tags\"><li>Cancro do pulm\u00e3o<\/li><li>Sarcoma<\/li><li>Carcinoma de c\u00e9lulas renais<\/li><\/ul><\/div>\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<section class=\"wp-block-group aa-section aa-section--cream aa-tp-symptoms is-layout-flow wp-block-group-is-layout-flow\" id=\"symptoms\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group aa-centered-head is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">04<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">Sintomas<\/h2>\n\t\t\t<div class=\"aa-divider-dot\"><\/div>\n\t\t\t<p class=\"wp-block-paragraph\">Os primeiros sinais s\u00e3o vagos e f\u00e1ceis de atribuir a outra coisa. Quando se tornam evidentes, os rins est\u00e3o geralmente j\u00e1 afetados.<\/p>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-organs aa-tp-organs--major is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<div class=\"wp-block-group aa-tp-organ is-layout-flow wp-block-group-is-layout-flow\"><h3 class=\"wp-block-heading\">Rins<\/h3><p class=\"aa-tp-organ__tag wp-block-paragraph\">O envolvimento principal<\/p><p class=\"wp-block-paragraph\">Tornozelos inchados, urina espumosa e um cansa\u00e7o que o repouso n\u00e3o alivia. As an\u00e1lises ao sangue mostram que os rins j\u00e1 n\u00e3o filtram corretamente. A insufici\u00eancia renal avan\u00e7ada \u00e9 a complica\u00e7\u00e3o mais grave da doen\u00e7a e pode levar \u00e0 di\u00e1lise.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-tp-organ is-layout-flow wp-block-group-is-layout-flow\"><h3 class=\"wp-block-heading\">Tubo digestivo<\/h3><p class=\"aa-tp-organ__tag wp-block-paragraph\">Est\u00f4mago e intestinos<\/p><p class=\"wp-block-paragraph\">A diarreia \u00e9 a queixa mais frequente. Pode surgir sangue nas fezes. O apetite diminui, e perde-se peso sem qualquer mudan\u00e7a volunt\u00e1ria na alimenta\u00e7\u00e3o.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-tp-organ is-layout-flow wp-block-group-is-layout-flow\"><h3 class=\"wp-block-heading\">F\u00edgado<\/h3><p class=\"aa-tp-organ__tag wp-block-paragraph\">Muitas vezes silencioso<\/p><p class=\"wp-block-paragraph\">O f\u00edgado aumenta de volume. Curiosamente, as enzimas hep\u00e1ticas mant\u00eam-se muitas vezes normais, ou pouco elevadas, o que explica em parte que o envolvimento possa passar despercebido durante muito tempo.<\/p><\/div>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-organs aa-tp-organs--minor is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<div class=\"wp-block-group aa-tp-organ is-layout-flow wp-block-group-is-layout-flow\"><h3 class=\"wp-block-heading\">Tiroide e bexiga<\/h3><p class=\"wp-block-paragraph\">Alguns doentes desenvolvem b\u00f3cio, um aumento de volume da tiroide. Quando a bexiga \u00e9 afetada, pode surgir sangue na urina.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-tp-organ is-layout-flow wp-block-group-is-layout-flow\"><h3 class=\"wp-block-heading\">Cora\u00e7\u00e3o<\/h3><p class=\"wp-block-paragraph\">\u00c9 aqui que a amiloidose AA se distingue claramente da amiloidose AL. Podem existir dep\u00f3sitos no cora\u00e7\u00e3o, mas os sinais de insufici\u00eancia card\u00edaca est\u00e3o geralmente ausentes.<\/p><\/div>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-flags is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-tp-flags__photo is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-doctor-reviewing-medical-imaging-on-a-lightbox-1024x683.jpg\" alt=\"Um m&#xE9;dico a examinar imagens m&#xE9;dicas num negatosc&#xF3;pio\" class=\"wp-image-703\" srcset=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-doctor-reviewing-medical-imaging-on-a-lightbox-1024x683.jpg 1024w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-doctor-reviewing-medical-imaging-on-a-lightbox-300x200.jpg 300w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-doctor-reviewing-medical-imaging-on-a-lightbox-768x512.jpg 768w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-doctor-reviewing-medical-imaging-on-a-lightbox-1536x1024.jpg 1536w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-tp-flags__body is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<h3 class=\"wp-block-heading\">Quando procurar aconselhamento<\/h3>\n\t\t\t\t<p class=\"wp-block-paragraph\">Se vive com uma doen\u00e7a inflamat\u00f3ria de longa dura\u00e7\u00e3o, estes s\u00e3o os sinais que conv\u00e9m referir ao m\u00e9dico que a acompanha.<\/p>\n\t\t\t\t\n\t\t\t\t<ul class=\"wp-block-list aa-tp-flags__list\">\n\t\t\t\t\t<li>P\u00e9s e tornozelos inchados<\/li>\n\t\t\t\t\t<li>Urina espumosa<\/li>\n\t\t\t\t\t<li>Cansa\u00e7o que o repouso n\u00e3o alivia<\/li>\n\t\t\t\t\t<li>Tens\u00e3o arterial baixa<\/li>\n\t\t\t\t\t<li>N\u00e1useas e v\u00f3mitos<\/li>\n\t\t\t\t\t<li>Pele seca e com comich\u00e3o<\/li>\n\t\t\t\t\t<li>C\u00e3ibras musculares<\/li>\n\t\t\t\t\t<li>Perda de apetite<\/li>\n\t\t\t\t\t<li>Diarreia, ou sangue nas fezes<\/li>\n\t\t\t\t<\/ul>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t<div class=\"wp-block-group aa-tp-alert is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t\t<p class=\"wp-block-paragraph\">Detetada cedo, a les\u00e3o renal pode ser travada. \u00c9 esse todo o sentido do rastreio.<\/p>\n\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<section class=\"wp-block-group aa-section aa-section--white aa-tp-dx is-layout-flow wp-block-group-is-layout-flow\" id=\"diagnosis\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-dx__body is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">05<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">Como se diagnostica a amiloidose AA<\/h2>\n\t\t\t<p class=\"aa-tp-dx__intro wp-block-paragraph\">Os sintomas assemelham-se aos de doen\u00e7as muito mais frequentes dos rins, do cora\u00e7\u00e3o, dos pulm\u00f5es e do f\u00edgado. Muitos doentes consultam v\u00e1rios m\u00e9dicos antes de o diagn\u00f3stico ser finalmente feito, da\u00ed a import\u00e2ncia das etapas seguintes.<\/p>\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-tp-dx__steps is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<div class=\"wp-block-group aa-tp-dx__step is-layout-flow wp-block-group-is-layout-flow\"><p class=\"aa-tp-dx__step-num wp-block-paragraph\">01<\/p><h4 class=\"wp-block-heading\">Confirmar com uma bi\u00f3psia<\/h4><p class=\"wp-block-paragraph\">S\u00f3 uma bi\u00f3psia permite ter a certeza. O tecido renal \u00e9 examinado ao microsc\u00f3pio \u00e0 procura de dep\u00f3sitos amiloides.<\/p><\/div>\n\t\t\t\t<div class=\"wp-block-group aa-tp-dx__step is-layout-flow wp-block-group-is-layout-flow\"><p class=\"aa-tp-dx__step-num wp-block-paragraph\">02<\/p><h4 class=\"wp-block-heading\">Tipar os dep\u00f3sitos<\/h4><p class=\"wp-block-paragraph\">Os dep\u00f3sitos s\u00e3o depois tipados, para confirmar que a subst\u00e2ncia amiloide \u00e9 realmente formada pela prote\u00edna SAA e n\u00e3o por outro precursor.<\/p><\/div>\n\t\t\t\t<div class=\"wp-block-group aa-tp-dx__step is-layout-flow wp-block-group-is-layout-flow\"><p class=\"aa-tp-dx__step-num wp-block-paragraph\">03<\/p><h4 class=\"wp-block-heading\">Medir a inflama\u00e7\u00e3o<\/h4><p class=\"wp-block-paragraph\">Doseiam-se a SAA circulante e a prote\u00edna C-reativa (PCR). Os resultados anteriores de PCR s\u00e3o tamb\u00e9m revistos: revelam h\u00e1 quanto tempo dura a inflama\u00e7\u00e3o.<\/p><\/div>\n\t\t\t\t<div class=\"wp-block-group aa-tp-dx__step is-layout-flow wp-block-group-is-layout-flow\"><p class=\"aa-tp-dx__step-num wp-block-paragraph\">04<\/p><h4 class=\"wp-block-heading\">Avaliar os \u00f3rg\u00e3os<\/h4><p class=\"wp-block-paragraph\">As an\u00e1lises ao sangue e \u00e0 urina medem a fun\u00e7\u00e3o renal, e o cora\u00e7\u00e3o \u00e9 tamb\u00e9m examinado. Em conjunto, mostram at\u00e9 onde os dep\u00f3sitos avan\u00e7aram.<\/p><\/div>\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-dx__photo is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-pipette-filling-a-laboratory-sample-vial-1024x683.jpg\" alt=\"Uma pipeta a encher um frasco de amostra de laborat&#xF3;rio\" class=\"wp-image-704\" srcset=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-pipette-filling-a-laboratory-sample-vial-1024x683.jpg 1024w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-pipette-filling-a-laboratory-sample-vial-300x200.jpg 300w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-pipette-filling-a-laboratory-sample-vial-768x512.jpg 768w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-pipette-filling-a-laboratory-sample-vial-1536x1024.jpg 1536w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<section class=\"wp-block-group aa-section aa-section--cream aa-treating is-layout-flow wp-block-group-is-layout-flow\" id=\"treatment\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group aa-centered-head is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">06<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">Tratamento<\/h2>\n\t\t\t<div class=\"aa-divider-dot\"><\/div>\n\t\t\t<p class=\"wp-block-paragraph\">O tratamento tem como objetivo controlar a doen\u00e7a inflamat\u00f3ria ou infecciosa subjacente e reduzir a produ\u00e7\u00e3o de prote\u00edna amiloide A s\u00e9rica (SAA), a prote\u00edna precursora que forma os dep\u00f3sitos amiloides AA.<\/p>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-treat-lead is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-tp-treat-lead__photo is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"745\" src=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/medicine-vials-and-ampoules-1024x745.jpg\" alt=\"Frascos e ampolas de medicamentos\" class=\"wp-image-705\" srcset=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/medicine-vials-and-ampoules-1024x745.jpg 1024w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/medicine-vials-and-ampoules-300x218.jpg 300w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/medicine-vials-and-ampoules-768x559.jpg 768w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/medicine-vials-and-ampoules-1536x1117.jpg 1536w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-tp-treat-lead__body is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<h3 class=\"wp-block-heading\">Tratar a causa, n\u00e3o os dep\u00f3sitos<\/h3>\n\t\t\t\t<p class=\"wp-block-paragraph\">O objetivo \u00e9 reduzir o excesso de SAA mal dobrada, impedindo o f\u00edgado de a produzir em excesso. S\u00f3 h\u00e1 uma forma de o conseguir: controlar a doen\u00e7a inflamat\u00f3ria subjacente.<\/p>\n\t\t\t\t<p class=\"wp-block-paragraph\">\u00c9 preciso diz\u00ea-lo com clareza: nenhum tratamento permite atualmente eliminar as fibrilhas amiloides depois de formadas. O que j\u00e1 est\u00e1 depositado permanece. \u00c9 precisamente por isso que agir cedo, e rastrear as pessoas em risco, muda a evolu\u00e7\u00e3o da doen\u00e7a.<\/p>\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-treating-grid is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<div class=\"wp-block-group aa-treating-card is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-icon-tile\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M10.5 20.5 3.5 13.5a5 5 0 0 1 7-7l7 7a5 5 0 0 1-7 7Z\"><\/path><path d=\"m8.5 8.5 7 7\"><\/path><\/svg><\/span><h3 class=\"wp-block-heading\">Febre mediterr\u00e2nica familiar<\/h3><p class=\"wp-block-paragraph\">Um anti-inflamat\u00f3rio di\u00e1rio, tomado para toda a vida. Suprime os surtos inflamat\u00f3rios repetidos e, com eles, o aumento da SAA.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-treating-card is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-icon-tile\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M12 22s8-4 8-10V5l-8-3-8 3v7c0 6 8 10 8 10z\"><\/path><\/svg><\/span><h3 class=\"wp-block-heading\">Infe\u00e7\u00f5es cr\u00f3nicas<\/h3><p class=\"wp-block-paragraph\">Antibi\u00f3ticos, para eliminar a infe\u00e7\u00e3o que mantinha a resposta inflamat\u00f3ria.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-treating-card is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-icon-tile\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><circle cx=\"12\" cy=\"12\" r=\"10\"><\/circle><circle cx=\"12\" cy=\"12\" r=\"6\"><\/circle><circle cx=\"12\" cy=\"12\" r=\"2\"><\/circle><\/svg><\/span><h3 class=\"wp-block-heading\">Doen\u00e7a inflamat\u00f3ria<\/h3><p class=\"wp-block-paragraph\">Corticosteroides ou terap\u00eauticas biol\u00f3gicas, escolhidos consoante a doen\u00e7a e a sua resposta ao tratamento.<\/p><\/div>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-support is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<h4 class=\"wp-block-heading\">Quando os rins falham<\/h4>\n\t\t\t<p class=\"wp-block-paragraph\">Na insufici\u00eancia renal terminal, o transplante \u00e9 poss\u00edvel nos doentes que, de resto, est\u00e3o de boa sa\u00fade. Entretanto, pode ser necess\u00e1ria a di\u00e1lise. Nenhum dos dois elimina a subst\u00e2ncia amiloide, mas ambos d\u00e3o o tempo de que o controlo da inflama\u00e7\u00e3o precisa.<\/p>\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<section class=\"wp-block-group aa-section aa-section--forest aa-tp-outlook is-layout-flow wp-block-group-is-layout-flow\" id=\"follow-up\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-outlook__photo is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/two-people-holding-hands-1024x683.jpg\" alt=\"Duas pessoas de m&#xE3;os dadas\" class=\"wp-image-706\" srcset=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/two-people-holding-hands-1024x683.jpg 1024w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/two-people-holding-hands-300x200.jpg 300w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/two-people-holding-hands-768x512.jpg 768w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/two-people-holding-hands-1536x1024.jpg 1536w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-outlook__body is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">07<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">Preven\u00e7\u00e3o e acompanhamento<\/h2>\n\t\t\t<h4 class=\"wp-block-heading\">Rastreio<\/h4>\n\t\t\t<p class=\"wp-block-paragraph\">A preven\u00e7\u00e3o \u00e9 sobretudo importante para as pessoas que vivem desde a inf\u00e2ncia com uma doen\u00e7a autoinflamat\u00f3ria gen\u00e9tica. Precisam de um tratamento anti-inflamat\u00f3rio para toda a vida e de um controlo uma vez por ano, para detetar a amiloidose antes que cause danos.<\/p>\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-aa-screening is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<p class=\"aa-aa-screening__label wp-block-paragraph\">Uma vez por ano<\/p>\n\t\t\t\t\n\t\t\t\t<div class=\"wp-block-group aa-aa-screening__items is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t\t<p class=\"aa-aa-screening__item wp-block-paragraph\">Uma an\u00e1lise \u00e0 urina, para detetar uma perda de prote\u00ednas pelos rins<\/p>\n\t\t\t\t\t<p class=\"aa-aa-screening__item wp-block-paragraph\">Uma an\u00e1lise ao sangue, para medir a inflama\u00e7\u00e3o e a fun\u00e7\u00e3o renal<\/p>\n\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t\t<h4 class=\"wp-block-heading\">Um acompanhamento partilhado<\/h4>\n\t\t\t<p class=\"wp-block-paragraph\">Uma vez confirmada a amiloidose AA, o acompanhamento \u00e9 pr\u00f3ximo e envolve v\u00e1rias pessoas ao mesmo tempo: o m\u00e9dico que trata a doen\u00e7a inflamat\u00f3ria subjacente, o seu m\u00e9dico de fam\u00edlia e um especialista em amiloidose AA. Cada um v\u00ea uma parte diferente do quadro.<\/p>\n\t\t\t<p class=\"aa-tp-outlook__closing wp-block-paragraph\">Alguns casos de amiloidose AA podem ser prevenidos atrav\u00e9s de um controlo precoce e sustentado da doen\u00e7a inflamat\u00f3ria ou infecciosa subjacente. \u00c9 isso que torna \u00fatil o controlo anual.<\/p>\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<section class=\"wp-block-group aa-section aa-section--white aa-tp-faq is-layout-flow wp-block-group-is-layout-flow\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group aa-centered-head is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">FAQ<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">Perguntas frequentes<\/h2>\n\t\t\t<div class=\"aa-divider-dot\"><\/div>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-acc is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\n\t\t\t<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>A amiloidose AA \u00e9 heredit\u00e1ria?<\/summary>\n\t\t\t<p class=\"wp-block-paragraph\">A amiloidose AA em si n\u00e3o \u00e9 heredit\u00e1ria, mas algumas das doen\u00e7as que a provocam s\u00e3o. A febre mediterr\u00e2nica familiar, a CAPS, a MKD e a TRAPS s\u00e3o doen\u00e7as autoinflamat\u00f3rias gen\u00e9ticas, que podem ocorrer em v\u00e1rias pessoas da mesma fam\u00edlia. Se uma delas foi diagnosticada na sua fam\u00edlia, pergunte ao seu m\u00e9dico se os seus familiares devem ser avaliados.<\/p>\n\t\t\t<\/details>\n\t\t\t\n\t\t\t\n\t\t\t<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>\u00c9 poss\u00edvel prevenir a amiloidose AA?<\/summary>\n\t\t\t<p class=\"wp-block-paragraph\">Em grande medida, sim, e \u00e9 isso que distingue a amiloidose AA das outras formas. Manter controlada a inflama\u00e7\u00e3o subjacente mant\u00e9m baixos os n\u00edveis de SAA, e sem excesso de SAA n\u00e3o h\u00e1 mat\u00e9ria-prima para a subst\u00e2ncia amiloide. Para as pessoas com uma doen\u00e7a autoinflamat\u00f3ria gen\u00e9tica, a preven\u00e7\u00e3o, na pr\u00e1tica, consiste num tratamento para toda a vida e num controlo anual.<\/p>\n\t\t\t<\/details>\n\t\t\t\n\t\t\t\n\t\t\t<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>O tratamento elimina os dep\u00f3sitos?<\/summary>\n\t\t\t<p class=\"wp-block-paragraph\">N\u00e3o. Nenhum tratamento atualmente dispon\u00edvel elimina as fibrilhas amiloides j\u00e1 formadas. O tratamento impede a forma\u00e7\u00e3o de novas fibrilhas, o que permite aos \u00f3rg\u00e3os estabilizar e, em alguns casos, recuperar parte da sua fun\u00e7\u00e3o. O que j\u00e1 est\u00e1 depositado permanece.<\/p>\n\t\t\t<\/details>\n\t\t\t\n\t\t\t\n\t\t\t<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>A amiloidose AA afeta o cora\u00e7\u00e3o?<\/summary>\n\t\t\t<p class=\"wp-block-paragraph\">Podem existir dep\u00f3sitos no cora\u00e7\u00e3o mas, ao contr\u00e1rio da amiloidose AL, os sinais de insufici\u00eancia card\u00edaca est\u00e3o geralmente ausentes. Na amiloidose AA, s\u00e3o os rins, e n\u00e3o o cora\u00e7\u00e3o, que dominam o quadro cl\u00ednico.<\/p>\n\t\t\t<\/details>\n\t\t\t\n\t\t\t\n\t\t\t<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>O que \u00e9 a SAA?<\/summary>\n\t\t\t<p class=\"wp-block-paragraph\">A prote\u00edna amiloide A s\u00e9rica \u00e9 uma prote\u00edna produzida pelo f\u00edgado. Circula no sangue em baixa concentra\u00e7\u00e3o, e a sua produ\u00e7\u00e3o aumenta como parte da resposta normal do organismo \u00e0 inflama\u00e7\u00e3o. Na amiloidose AA, uma inflama\u00e7\u00e3o que nunca se apaga mant\u00e9m a SAA elevada durante anos, at\u00e9 que parte dela se dobra mal e forma dep\u00f3sitos.<\/p>\n\t\t\t<\/details>\n\t\t\t\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-disclaimer is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"wp-block-paragraph\">Esta p\u00e1gina destina-se a fornecer informa\u00e7\u00e3o geral a doentes, fam\u00edlias e profissionais de sa\u00fade. N\u00e3o substitui o aconselhamento m\u00e9dico. Fale sempre da sua situa\u00e7\u00e3o com a sua equipa de especialistas.<\/p>\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<section class=\"wp-block-group aa-next aa-next--split is-layout-flow wp-block-group-is-layout-flow\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group aa-next__head is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">Continuar<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">Outros tipos<\/h2>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-next__grid is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<div class=\"wp-block-group aa-next-card is-layout-flow wp-block-group-is-layout-flow\"><h3 class=\"wp-block-heading\"><a href=\"https:\/\/www.amyloidosisalliance.org\/pt\/tipos-de-amiloidose\/amiloidose-al\/\">Amiloidose AL<\/a><\/h3><p class=\"wp-block-paragraph\">A forma sist\u00e9mica mais frequente, causada por cadeias leves produzidas na medula \u00f3ssea.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-next-card is-layout-flow wp-block-group-is-layout-flow\"><h3 class=\"wp-block-heading\"><a href=\"https:\/\/www.amyloidosisalliance.org\/pt\/tipos-de-amiloidose\/amiloidose-attr\/\">Amiloidose ATTR<\/a><\/h3><p class=\"wp-block-paragraph\">Causada pela transtirretina, heredit\u00e1ria na ATTRv, associada \u00e0 idade na ATTRwt.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-next-card is-layout-flow wp-block-group-is-layout-flow\"><h3 class=\"wp-block-heading\"><a href=\"https:\/\/www.amyloidosisalliance.org\/pt\/tipos-de-amiloidose\/outros-tipos\/\">Outros tipos<\/a><\/h3><p class=\"wp-block-paragraph\">As formas heredit\u00e1rias raras, e a amiloidose localizada, limitada a um \u00fanico local.<\/p><\/div>\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n","protected":false},"excerpt":{"rendered":"<p>In\u00edcio\u203aAmiloidose\u203aTipos de amiloidose\u203aAmiloidose AA Tipos de amiloidose Amiloidose AA A amiloidose AA \u00e9 uma complica\u00e7\u00e3o de uma inflama\u00e7\u00e3o de longa dura\u00e7\u00e3o. N\u00e3o \u00e9 heredit\u00e1ria nem \u00e9 um cancro do sangue: desenvolve-se quando outra doen\u00e7a mant\u00e9m o organismo inflamado durante anos. \u00c9 ao controlar essa doen\u00e7a que se trava, o que faz da amiloidose AA a [&hellip;]<\/p>\n","protected":false},"author":0,"featured_media":0,"parent":3121,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-3115","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Amiloidose AA: causas, sintomas e tratamento<\/title>\n<meta name=\"description\" content=\"A amiloidose AA surge ap\u00f3s anos de inflama\u00e7\u00e3o n\u00e3o tratada. 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