{"id":1740,"date":"2023-05-02T08:10:42","date_gmt":"2023-05-02T06:10:42","guid":{"rendered":"https:\/\/amyloidosisalliance.local\/ou-en-est-la-recherche-sur-lamylose\/"},"modified":"2026-09-29T15:32:19","modified_gmt":"2026-09-29T13:32:19","slug":"ou-en-est-la-recherche-sur-lamylose","status":"publish","type":"post","link":"https:\/\/www.amyloidosisalliance.org\/fr\/ou-en-est-la-recherche-sur-lamylose\/","title":{"rendered":"O\u00f9 en est la recherche sur l\u2019amylose\u202f?"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">L\u2019amylose est une maladie r\u00e9cente, d\u00e9crite pour la premi\u00e8re fois en 1838 par Rudolph Virchow, un anatomopathologiste allemand, qui avait identifi\u00e9 des d\u00e9p\u00f4ts anormaux dans les tissus de patients d\u00e9c\u00e9d\u00e9s. Depuis, de nombreuses recherches ont \u00e9t\u00e9 men\u00e9es pour comprendre comment se forment les prot\u00e9ines amylo\u00efdes, identifier les facteurs de risque de l\u2019amylose et d\u00e9velopper de nouveaux traitements pour cette maladie rare. M\u00eame si la recherche sur l\u2019amylose reste relativement limit\u00e9e, les avanc\u00e9es r\u00e9centes apportent de l\u2019espoir aux patients. Mais o\u00f9 en est la recherche sur l\u2019amylose\u202f? C\u2019est la question \u00e0 laquelle nous tentons de r\u00e9pondre dans cet article.<\/p>\n\n<h2 class=\"wp-block-heading\">Les causes et les traitements de l\u2019amylose<\/h2>\n\n<p class=\"wp-block-paragraph\">Les causes de l\u2019amylose sont encore mal comprises, mais les scientifiques ont d\u00e9couvert que la maladie peut \u00eatre h\u00e9r\u00e9ditaire et que ses sympt\u00f4mes d\u00e9pendent de l\u2019organe touch\u00e9, et varient donc d\u2019un patient \u00e0 l\u2019autre. Il existe aujourd\u2019hui peu de traitements de l\u2019amylose, ce qui rend la recherche sur cette maladie d\u2019autant plus importante. Pour d\u00e9velopper de nouveaux traitements, les scientifiques cherchent \u00e0 comprendre les m\u00e9canismes de l\u2019amylose\u00a0: un d\u00e9fi majeur.<\/p>\n\n<p class=\"wp-block-paragraph\">La recherche vise \u00e0 comprendre comment la maladie se d\u00e9veloppe\u00a0:<\/p>\n\n<ul class=\"wp-block-list\">\n<li>Pourquoi certains organes sont-ils plus touch\u00e9s que d\u2019autres\u202f?<\/li>\n\n\n\n<li>Lorsqu\u2019une mutation g\u00e9n\u00e9tique est pr\u00e9sente, pourquoi certains membres de la famille d\u00e9veloppent-ils la maladie et d\u2019autres non\u202f?<\/li>\n\n\n\n<li>Au-del\u00e0 de la g\u00e9n\u00e9tique, quelles autres causes peuvent d\u00e9clencher la maladie\u202f?<\/li>\n<\/ul>\n\n<p class=\"wp-block-paragraph\">Autant de questions auxquelles la science tente d\u2019apporter des r\u00e9ponses concr\u00e8tes et fiables. Chaque patient peut apporter sa pierre \u00e0 l\u2019\u00e9difice, simplement en en parlant avec son m\u00e9decin.<\/p>\n\n<h2 class=\"wp-block-heading\">Les avanc\u00e9es de la recherche<\/h2>\n\n<p class=\"wp-block-paragraph\">La recherche permet de d\u00e9velopper de nouveaux traitements. De nouvelles chimioth\u00e9rapies et de nouveaux protocoles ont r\u00e9cemment \u00e9t\u00e9 propos\u00e9s pour traiter l\u2019amylose AL. La collaboration internationale a permis l\u2019arriv\u00e9e r\u00e9cente de nouveaux traitements, tandis que d\u2019autres m\u00e9dicaments sont en cours d\u2019\u00e9valuation.<\/p>\n\n<p class=\"wp-block-paragraph\">La recherche porte aujourd\u2019hui sur deux axes\u00a0:<\/p>\n\n<ul class=\"wp-block-list\">\n<li>les enzymes et leur r\u00f4le dans la formation de la substance amylo\u00efde<\/li>\n\n\n\n<li>la recherche de biomarqueurs de l\u2019amylose.<\/li>\n<\/ul>\n\n<p class=\"wp-block-paragraph\">Les avanc\u00e9es r\u00e9centes de la recherche sur cette maladie sont donc encourageantes, et les scientifiques qui travaillent dur pour comprendre et traiter cette maladie m\u00e9ritent d\u2019\u00eatre encourag\u00e9s.<\/p>\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n<p class=\"wp-block-paragraph\">Pour r\u00e9pondre \u00e0 la question \u00ab\u00a0O\u00f9 en est la recherche sur l\u2019amylose\u202f?\u00a0\u00bb, cet article s\u2019est inspir\u00e9 des fiches questions-r\u00e9ponses de Jodie (en fran\u00e7ais).<\/p>\n<p><img decoding=\"async\" width=\"1024\" height=\"1024\" src=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2023\/04\/fiche-de-Jodie-2-1024x1024.jpg\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2023\/04\/fiche-de-Jodie-2-1024x1024.jpg 1024w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2023\/04\/fiche-de-Jodie-2-300x300.jpg 300w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2023\/04\/fiche-de-Jodie-2-150x150.jpg 150w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2023\/04\/fiche-de-Jodie-2-768x768.jpg 768w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2023\/04\/fiche-de-Jodie-2-250x250.jpg 250w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2023\/04\/fiche-de-Jodie-2.jpg 1080w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\"><br \/>\n\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1024\" height=\"1024\" src=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2023\/04\/fiche-de-Jodie-3-1024x1024.jpg\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2023\/04\/fiche-de-Jodie-3-1024x1024.jpg 1024w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2023\/04\/fiche-de-Jodie-3-300x300.jpg 300w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2023\/04\/fiche-de-Jodie-3-150x150.jpg 150w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2023\/04\/fiche-de-Jodie-3-768x768.jpg 768w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2023\/04\/fiche-de-Jodie-3-250x250.jpg 250w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2023\/04\/fiche-de-Jodie-3.jpg 1080w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>D\u00e9crite pour la premi\u00e8re fois en 1838, l\u2019amylose reste un domaine de recherche jeune. Un point sur ce que l\u2019on sait de ses causes, des traitements actuels et de la recherche.<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[24],"tags":[],"class_list":["post-1740","post","type-post","status-publish","format-standard","hentry","category-actualites"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>O\u00f9 en est la recherche sur l\u2019amylose\u202f?<\/title>\n<meta name=\"description\" content=\"D\u00e9crite pour la premi\u00e8re fois en 1838, l\u2019amylose reste un domaine de recherche jeune. 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