{"id":1419,"date":"2026-07-10T14:54:26","date_gmt":"2026-07-10T12:54:26","guid":{"rendered":"https:\/\/amyloidosisalliance.local\/amylose-aa\/"},"modified":"2026-09-29T11:03:56","modified_gmt":"2026-09-29T09:03:56","slug":"amylose-aa","status":"publish","type":"page","link":"https:\/\/www.amyloidosisalliance.org\/fr\/types-damylose\/amylose-aa\/","title":{"rendered":"Amylose AA"},"content":{"rendered":"\n<nav class=\"wp-block-group aa-breadcrumb aa-events-hero__crumb is-layout-flow wp-block-group-is-layout-flow\" aria-label=\"Breadcrumb\">\n\t\n\t<div class=\"aa-inner\"><a href=\"\/\">Accueil<\/a><span class=\"aa-breadcrumb__sep\">\u203a<\/span><span class=\"aa-breadcrumb__label\">Amylose<\/span><span class=\"aa-breadcrumb__sep\">\u203a<\/span><a href=\"https:\/\/www.amyloidosisalliance.org\/fr\/types-damylose\/\">Types d\u2019amylose<\/a><span class=\"aa-breadcrumb__sep\">\u203a<\/span><span class=\"aa-breadcrumb__current\">Amylose AA<\/span><\/div>\n\t\n<\/nav>\n\n<section class=\"wp-block-group aa-events-hero aa-events-hero--art aa-events-hero--aa is-layout-flow wp-block-group-is-layout-flow\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t<p class=\"aa-events-hero__kicker wp-block-paragraph\">Types d\u2019amylose<\/p>\n\t\t<h1 class=\"wp-block-heading\">Amylose AA<\/h1>\n\t\t<p class=\"wp-block-paragraph\">L\u2019amylose AA est une complication d\u2019une inflammation de longue dur\u00e9e. Elle n\u2019est pas h\u00e9r\u00e9ditaire, et ce n\u2019est pas un cancer du sang\u00a0: elle se d\u00e9veloppe lorsqu\u2019une autre maladie entretient une inflammation dans l\u2019organisme pendant des ann\u00e9es. C\u2019est en contr\u00f4lant cette maladie qu\u2019on l\u2019arr\u00eate, ce qui fait de l\u2019amylose AA la seule forme d\u2019amylose que l\u2019on peut r\u00e9ellement pr\u00e9venir.<\/p>\n\t<\/div>\n\t\n\t\n\t<div class=\"wp-block-group aa-events-hero__art is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"\/wp-content\/themes\/amyloidosis-alliance\/assets\/images\/disease\/aa.svg\" alt=\"Sch&#xE9;ma&#xA0;: une inflammation chronique produit une prot&#xE9;ine qui se replie mal, s&#x2019;aligne et s&#x2019;empile en une fibrille amylo&#xEF;de\"\/><\/figure>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<nav class=\"wp-block-group aa-anchorband is-layout-flow wp-block-group-is-layout-flow\" aria-label=\"Section navigation\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-columns aa-anchor-cols is-layout-flex wp-container-core-columns-is-layout-b2e659ba wp-block-columns-is-layout-flex\">\n\t\t\t<div class=\"wp-block-column aa-anchor-item is-layout-flow wp-block-column-is-layout-flow\"><p class=\"num wp-block-paragraph\">01<\/p><p class=\"lbl wp-block-paragraph\"><a href=\"#what\">Qu\u2019est-ce que l\u2019AA\u202f?<\/a><\/p><\/div>\n\t\t\t<div class=\"wp-block-column aa-anchor-item is-layout-flow wp-block-column-is-layout-flow\"><p class=\"num wp-block-paragraph\">02<\/p><p class=\"lbl wp-block-paragraph\"><a href=\"#causes\">Comment elle se d\u00e9veloppe<\/a><\/p><\/div>\n\t\t\t<div class=\"wp-block-column aa-anchor-item is-layout-flow wp-block-column-is-layout-flow\"><p class=\"num wp-block-paragraph\">03<\/p><p class=\"lbl wp-block-paragraph\"><a href=\"#conditions\">Causes sous-jacentes<\/a><\/p><\/div>\n\t\t\t<div class=\"wp-block-column aa-anchor-item is-layout-flow wp-block-column-is-layout-flow\"><p class=\"num wp-block-paragraph\">04<\/p><p class=\"lbl wp-block-paragraph\"><a href=\"#symptoms\">Sympt\u00f4mes<\/a><\/p><\/div>\n\t\t\t<div class=\"wp-block-column aa-anchor-item is-layout-flow wp-block-column-is-layout-flow\"><p class=\"num wp-block-paragraph\">05<\/p><p class=\"lbl wp-block-paragraph\"><a href=\"#diagnosis\">Diagnostic<\/a><\/p><\/div>\n\t\t\t<div class=\"wp-block-column aa-anchor-item is-layout-flow wp-block-column-is-layout-flow\"><p class=\"num wp-block-paragraph\">06<\/p><p class=\"lbl wp-block-paragraph\"><a href=\"#treatment\">Traitement<\/a><\/p><\/div>\n\t\t\t<div class=\"wp-block-column aa-anchor-item is-layout-flow wp-block-column-is-layout-flow\"><p class=\"num wp-block-paragraph\">07<\/p><p class=\"lbl wp-block-paragraph\"><a href=\"#follow-up\">Pr\u00e9vention<\/a><\/p><\/div>\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/nav>\n\n<section class=\"wp-block-group aa-section aa-section--white aa-what is-layout-flow wp-block-group-is-layout-flow\" id=\"what\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">01<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">Qu\u2019est-ce que l\u2019amylose AA\u202f?<\/h2>\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-key-idea is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<p class=\"aa-key-idea__label wp-block-paragraph\">\u00c0 retenir<\/p>\n\t\t\t\t<p class=\"wp-block-paragraph\">L\u2019amylose AA est une complication rare d\u2019une inflammation persistante, le plus souvent due \u00e0 une maladie inflammatoire ou infectieuse chronique. Trouvez l\u2019inflammation, traitez-la, et vous arr\u00eatez la substance amylo\u00efde \u00e0 la source.<\/p>\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-what-cols is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-what-col is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<h4 class=\"wp-block-heading\">Une prot\u00e9ine de l\u2019inflammation<\/h4>\n\t\t\t\t<p class=\"wp-block-paragraph\">La substance amylo\u00efde de l\u2019amylose AA est faite de <strong>prot\u00e9ine amylo\u00efde A s\u00e9rique<\/strong> (SAA), une prot\u00e9ine produite par le foie. Elle est normalement pr\u00e9sente dans le sang \u00e0 faible concentration, et sa production augmente fortement d\u00e8s que l\u2019organisme est en \u00e9tat d\u2019inflammation.<\/p>\n\t\t\t\t<p class=\"wp-block-paragraph\">Cette r\u00e9action est tout \u00e0 fait normale, et sans danger, tant qu\u2019elle est br\u00e8ve. Le probl\u00e8me commence lorsque l\u2019inflammation dure des ann\u00e9es plut\u00f4t que des semaines. La SAA circule alors en exc\u00e8s, se replie mal et s\u2019empile en fibrilles amylo\u00efdes insolubles.<\/p>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-what-col is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<h4 class=\"wp-block-heading\">Les organes qu\u2019elle atteint<\/h4>\n\t\t\t\t<p class=\"wp-block-paragraph\">Les <strong>reins<\/strong> avant tout\u00a0: ils sont touch\u00e9s chez la grande majorit\u00e9 des patients, et c\u2019est g\u00e9n\u00e9ralement un probl\u00e8me r\u00e9nal qui conduit au diagnostic.<\/p>\n\t\t\t\t<p class=\"wp-block-paragraph\">Les d\u00e9p\u00f4ts atteignent aussi le tube digestif, estomac et intestins, ainsi que le foie et les glandes salivaires. Toute maladie capable d\u2019entretenir une inflammation durable dans l\u2019organisme peut, en principe, conduire \u00e0 une amylose AA.<\/p>\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<section class=\"wp-block-group aa-section aa-section--cream aa-forms is-layout-flow wp-block-group-is-layout-flow\" id=\"causes\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group aa-centered-head is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">02<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">Comment l\u2019amylose AA se d\u00e9veloppe<\/h2>\n\t\t\t<div class=\"aa-divider-dot\"><\/div>\n\t\t\t<p class=\"wp-block-paragraph\">Quatre \u00e9tapes qui transforment une r\u00e9ponse immunitaire ordinaire en une maladie des organes.<\/p>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-proc-grid is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<div class=\"wp-block-group aa-proc-step is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-proc-step__icon\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M8.5 14.5A2.5 2.5 0 0 0 11 12c0-1.38-.5-2-1-3-1.07-2.14-.22-4.05 2-6 .5 2.5 2 4.9 4 6.5 2 1.6 3 3.5 3 5.5a7 7 0 1 1-14 0c0-1.15.43-2.29 1-3a2.5 2.5 0 0 0 2.5 2.5z\"><\/path><\/svg><\/span><p class=\"aa-proc-step__num wp-block-paragraph\">\u00c9tape 01<\/p><h4 class=\"wp-block-heading\">Inflammation chronique<\/h4><p class=\"wp-block-paragraph\">Une autre maladie entretient l\u2019inflammation dans l\u2019organisme\u00a0: une infection de longue dur\u00e9e, un rhumatisme inflammatoire, une maladie intestinale, un syndrome auto-inflammatoire.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-proc-step is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-proc-step__icon\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><polyline points=\"22 7 13.5 15.5 8.5 10.5 2 17\"><\/polyline><polyline points=\"16 7 22 7 22 13\"><\/polyline><\/svg><\/span><p class=\"aa-proc-step__num wp-block-paragraph\">\u00c9tape 02<\/p><h4 class=\"wp-block-heading\">Le foie fabrique la SAA<\/h4><p class=\"wp-block-paragraph\">En r\u00e9ponse, le foie augmente sa production de prot\u00e9ine amylo\u00efde A s\u00e9rique. Les taux sanguins restent \u00e9lev\u00e9s, non pas pendant quelques jours, mais pendant des ann\u00e9es.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-proc-step is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-proc-step__icon\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><polyline points=\"16 3 21 3 21 8\"><\/polyline><line x1=\"4\" y1=\"20\" x2=\"21\" y2=\"3\"><\/line><polyline points=\"21 16 21 21 16 21\"><\/polyline><line x1=\"15\" y1=\"15\" x2=\"21\" y2=\"21\"><\/line><line x1=\"4\" y1=\"4\" x2=\"9\" y2=\"9\"><\/line><\/svg><\/span><p class=\"aa-proc-step__num wp-block-paragraph\">\u00c9tape 03<\/p><h4 class=\"wp-block-heading\">Des fibrilles se forment<\/h4><p class=\"wp-block-paragraph\">Circulant en exc\u00e8s, la SAA se replie mal et s\u2019empile en fibrilles amylo\u00efdes insolubles que l\u2019organisme ne sait pas \u00e9liminer.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-proc-step is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-proc-step__icon\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M10.29 3.86L1.82 18a2 2 0 0 0 1.71 3h16.94a2 2 0 0 0 1.71-3L13.71 3.86a2 2 0 0 0-3.42 0z\"><\/path><line x1=\"12\" y1=\"9\" x2=\"12\" y2=\"13\"><\/line><line x1=\"12\" y1=\"17\" x2=\"12.01\" y2=\"17\"><\/line><\/svg><\/span><p class=\"aa-proc-step__num wp-block-paragraph\">\u00c9tape 04<\/p><h4 class=\"wp-block-heading\">D\u00e9p\u00f4ts dans les organes<\/h4><p class=\"wp-block-paragraph\">Les fibrilles se d\u00e9posent dans les tissus, en premier lieu dans les reins, et alt\u00e8rent progressivement leur fonctionnement.<\/p><\/div>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-alert aa-tp-alert--wide is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"wp-block-paragraph\">Dans l\u2019amylose AA, l\u2019inflammation est g\u00e9n\u00e9ralement pr\u00e9sente depuis plusieurs ann\u00e9es avant que la substance amylo\u00efde ne commence \u00e0 se former.<\/p>\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<section class=\"wp-block-group aa-section aa-section--white aa-treating is-layout-flow wp-block-group-is-layout-flow\" id=\"conditions\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group aa-centered-head is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">03<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">Ce qui entretient l\u2019inflammation<\/h2>\n\t\t\t<div class=\"aa-divider-dot\"><\/div>\n\t\t\t<p class=\"wp-block-paragraph\">L\u2019amylose AA n\u2019arrive jamais seule. Elle fait suite \u00e0 une autre maladie, et identifier laquelle est la premi\u00e8re \u00e9tape du traitement.<\/p>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-treating-grid is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<div class=\"wp-block-group aa-treating-card is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-icon-tile\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M17 10c.7-.7 1.69 0 2.5 0a2.5 2.5 0 1 0 0-5 .5.5 0 0 1-.5-.5 2.5 2.5 0 1 0-5 0c0 .81.7 1.8 0 2.5l-7 7c-.7.7-1.69 0-2.5 0a2.5 2.5 0 0 0 0 5c.28 0 .5.22.5.5a2.5 2.5 0 1 0 5 0c0-.81-.7-1.8 0-2.5Z\"><\/path><\/svg><\/span><h3 class=\"wp-block-heading\">Rhumatismes inflammatoires<\/h3><p class=\"wp-block-paragraph\">Les maladies articulaires qui maintiennent le syst\u00e8me immunitaire actif pendant des d\u00e9cennies figurent parmi les causes les plus fr\u00e9quentes.<\/p><ul class=\"wp-block-list aa-acc__tags\"><li>Polyarthrite rhumato\u00efde<\/li><li>Rhumatisme psoriasique<\/li><li>Spondyloarthrite<\/li><li>Goutte<\/li><\/ul><\/div>\n\t\t\t<div class=\"wp-block-group aa-treating-card is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-icon-tile\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M2 15c6.667-6 13.333 0 20-6\"><\/path><path d=\"M2 9c6.667 6 13.333 0 20 6\"><\/path><line x1=\"7\" y1=\"6\" x2=\"9\" y2=\"8\"><\/line><line x1=\"15\" y1=\"16\" x2=\"17\" y2=\"18\"><\/line><\/svg><\/span><h3 class=\"wp-block-heading\">Maladies auto-inflammatoires<\/h3><p class=\"wp-block-paragraph\">Des maladies g\u00e9n\u00e9tiques qui provoquent des pouss\u00e9es inflammatoires r\u00e9p\u00e9t\u00e9es, souvent d\u00e8s l\u2019enfance. Ce sont les patients pour qui le d\u00e9pistage compte le plus.<\/p><ul class=\"wp-block-list aa-acc__tags\"><li>Fi\u00e8vre m\u00e9diterran\u00e9enne familiale<\/li><li>CAPS<\/li><li>MKD<\/li><li>TRAPS<\/li><\/ul><\/div>\n\t\t\t<div class=\"wp-block-group aa-treating-card is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-icon-tile\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M4 3v10a4 4 0 0 0 8 0V7a3 3 0 0 1 6 0v8\"><\/path><circle cx=\"18\" cy=\"18\" r=\"3\"><\/circle><\/svg><\/span><h3 class=\"wp-block-heading\">Maladies inflammatoires chroniques de l\u2019intestin<\/h3><p class=\"wp-block-paragraph\">Une inflammation durable du tube digestif, lorsqu\u2019elle est mal contr\u00f4l\u00e9e pendant de nombreuses ann\u00e9es.<\/p><ul class=\"wp-block-list aa-acc__tags\"><li>Maladie de Crohn<\/li><li>Rectocolite h\u00e9morragique<\/li><\/ul><\/div>\n\t\t\t<div class=\"wp-block-group aa-treating-card is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-icon-tile\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M12 20c-3.3 0-6-2.7-6-6v-3a6 6 0 0 1 12 0v3c0 3.3-2.7 6-6 6z\"><\/path><path d=\"M12 20v-9\"><\/path><path d=\"M6 13H2\"><\/path><path d=\"M22 13h-4\"><\/path><path d=\"m8 2 1.9 1.9\"><\/path><path d=\"M16 2l-1.9 1.9\"><\/path><\/svg><\/span><h3 class=\"wp-block-heading\">Infections chroniques<\/h3><p class=\"wp-block-paragraph\">Des infections qui persistent au lieu de gu\u00e9rir, en particulier celles des poumons.<\/p><ul class=\"wp-block-list aa-acc__tags\"><li>Infections pulmonaires<\/li><\/ul><\/div>\n\t\t\t<div class=\"wp-block-group aa-treating-card is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-icon-tile\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M12 22a7 7 0 0 0 7-7c0-2-1-3.9-3-5.5s-3.5-4-4-6.5c-.5 2.5-2 4.9-4 6.5S5 13 5 15a7 7 0 0 0 7 7z\"><\/path><\/svg><\/span><h3 class=\"wp-block-heading\">Maladies du sang<\/h3><p class=\"wp-block-paragraph\">Certaines maladies h\u00e9matologiques entretiennent un \u00e9tat inflammatoire sur le long terme.<\/p><ul class=\"wp-block-list aa-acc__tags\"><li>My\u00e9lome<\/li><li>Lymphome non hodgkinien<\/li><li>Maladie de Castleman<\/li><\/ul><\/div>\n\t\t\t<div class=\"wp-block-group aa-treating-card is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-icon-tile\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M12 3l2.5 6.5L21 12l-6.5 2.5L12 21l-2.5-6.5L3 12l6.5-2.5z\"><\/path><\/svg><\/span><h3 class=\"wp-block-heading\">Tumeurs solides<\/h3><p class=\"wp-block-paragraph\">Une cause plus rare, mais reconnue. Certaines tumeurs entretiennent une inflammation chronique.<\/p><ul class=\"wp-block-list aa-acc__tags\"><li>Cancer du poumon<\/li><li>Sarcome<\/li><li>Carcinome \u00e0 cellules r\u00e9nales<\/li><\/ul><\/div>\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<section class=\"wp-block-group aa-section aa-section--cream aa-tp-symptoms is-layout-flow wp-block-group-is-layout-flow\" id=\"symptoms\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group aa-centered-head is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">04<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">Sympt\u00f4mes<\/h2>\n\t\t\t<div class=\"aa-divider-dot\"><\/div>\n\t\t\t<p class=\"wp-block-paragraph\">Les premiers signes sont vagues et faciles \u00e0 attribuer \u00e0 autre chose. Lorsqu\u2019ils deviennent \u00e9vidents, les reins sont g\u00e9n\u00e9ralement d\u00e9j\u00e0 touch\u00e9s.<\/p>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-organs aa-tp-organs--major is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<div class=\"wp-block-group aa-tp-organ is-layout-flow wp-block-group-is-layout-flow\"><h3 class=\"wp-block-heading\">Reins<\/h3><p class=\"aa-tp-organ__tag wp-block-paragraph\">L\u2019atteinte principale<\/p><p class=\"wp-block-paragraph\">Des chevilles qui gonflent, des urines mousseuses, et une fatigue que le repos ne soulage pas. Les analyses de sang montrent que les reins ne filtrent plus correctement. L\u2019insuffisance r\u00e9nale avanc\u00e9e est la complication la plus grave de la maladie, et peut conduire \u00e0 la dialyse.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-tp-organ is-layout-flow wp-block-group-is-layout-flow\"><h3 class=\"wp-block-heading\">Tube digestif<\/h3><p class=\"aa-tp-organ__tag wp-block-paragraph\">Estomac et intestins<\/p><p class=\"wp-block-paragraph\">La diarrh\u00e9e est la plainte la plus fr\u00e9quente. Du sang peut appara\u00eetre dans les selles. L\u2019app\u00e9tit diminue, et on perd du poids sans avoir chang\u00e9 volontairement d\u2019alimentation.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-tp-organ is-layout-flow wp-block-group-is-layout-flow\"><h3 class=\"wp-block-heading\">Foie<\/h3><p class=\"aa-tp-organ__tag wp-block-paragraph\">Souvent silencieuse<\/p><p class=\"wp-block-paragraph\">Le foie augmente de volume. Curieusement, les enzymes h\u00e9patiques restent souvent normales, ou \u00e0 peine \u00e9lev\u00e9es, ce qui explique en partie que l\u2019atteinte puisse passer longtemps inaper\u00e7ue.<\/p><\/div>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-organs aa-tp-organs--minor is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<div class=\"wp-block-group aa-tp-organ is-layout-flow wp-block-group-is-layout-flow\"><h3 class=\"wp-block-heading\">Thyro\u00efde et vessie<\/h3><p class=\"wp-block-paragraph\">Certains patients d\u00e9veloppent un goitre, une augmentation de volume de la thyro\u00efde. Lorsque la vessie est touch\u00e9e, du sang peut appara\u00eetre dans les urines.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-tp-organ is-layout-flow wp-block-group-is-layout-flow\"><h3 class=\"wp-block-heading\">C\u0153ur<\/h3><p class=\"wp-block-paragraph\">C\u2019est l\u00e0 que l\u2019amylose AA se distingue nettement de l\u2019amylose AL. Des d\u00e9p\u00f4ts peuvent \u00eatre pr\u00e9sents dans le c\u0153ur, mais les signes d\u2019insuffisance cardiaque sont g\u00e9n\u00e9ralement absents.<\/p><\/div>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-flags is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-tp-flags__photo is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-doctor-reviewing-medical-imaging-on-a-lightbox-1024x683.jpg\" alt=\"Un m&#xE9;decin examinant des images m&#xE9;dicales sur un n&#xE9;gatoscope\" class=\"wp-image-703\" srcset=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-doctor-reviewing-medical-imaging-on-a-lightbox-1024x683.jpg 1024w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-doctor-reviewing-medical-imaging-on-a-lightbox-300x200.jpg 300w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-doctor-reviewing-medical-imaging-on-a-lightbox-768x512.jpg 768w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-doctor-reviewing-medical-imaging-on-a-lightbox-1536x1024.jpg 1536w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-tp-flags__body is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<h3 class=\"wp-block-heading\">Quand consulter<\/h3>\n\t\t\t\t<p class=\"wp-block-paragraph\">Si vous vivez avec une maladie inflammatoire de longue dur\u00e9e, voici les signes \u00e0 signaler au m\u00e9decin qui la suit.<\/p>\n\t\t\t\t\n\t\t\t\t<ul class=\"wp-block-list aa-tp-flags__list\">\n\t\t\t\t\t<li>Des pieds et des chevilles gonfl\u00e9s<\/li>\n\t\t\t\t\t<li>Des urines mousseuses<\/li>\n\t\t\t\t\t<li>Une fatigue que le repos ne soulage pas<\/li>\n\t\t\t\t\t<li>Une tension art\u00e9rielle basse<\/li>\n\t\t\t\t\t<li>Naus\u00e9es et vomissements<\/li>\n\t\t\t\t\t<li>Une peau s\u00e8che qui d\u00e9mange<\/li>\n\t\t\t\t\t<li>Des crampes musculaires<\/li>\n\t\t\t\t\t<li>Une perte d\u2019app\u00e9tit<\/li>\n\t\t\t\t\t<li>Une diarrh\u00e9e, ou du sang dans les selles<\/li>\n\t\t\t\t<\/ul>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t<div class=\"wp-block-group aa-tp-alert is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t\t<p class=\"wp-block-paragraph\">Rep\u00e9r\u00e9e t\u00f4t, l\u2019atteinte r\u00e9nale peut \u00eatre stopp\u00e9e. C\u2019est tout l\u2019objet du d\u00e9pistage.<\/p>\n\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<section class=\"wp-block-group aa-section aa-section--white aa-tp-dx is-layout-flow wp-block-group-is-layout-flow\" id=\"diagnosis\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-dx__body is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">05<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">Comment l\u2019amylose AA est diagnostiqu\u00e9e<\/h2>\n\t\t\t<p class=\"aa-tp-dx__intro wp-block-paragraph\">Les sympt\u00f4mes ressemblent \u00e0 ceux de maladies bien plus fr\u00e9quentes des reins, du c\u0153ur, des poumons et du foie. De nombreux patients consultent plusieurs m\u00e9decins avant que le diagnostic ne soit enfin pos\u00e9, d\u2019o\u00f9 l\u2019importance des \u00e9tapes ci-dessous.<\/p>\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-tp-dx__steps is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<div class=\"wp-block-group aa-tp-dx__step is-layout-flow wp-block-group-is-layout-flow\"><p class=\"aa-tp-dx__step-num wp-block-paragraph\">01<\/p><h4 class=\"wp-block-heading\">Confirmer par une biopsie<\/h4><p class=\"wp-block-paragraph\">Seule une biopsie permet d\u2019en \u00eatre certain. Le tissu r\u00e9nal est examin\u00e9 au microscope \u00e0 la recherche de d\u00e9p\u00f4ts amylo\u00efdes.<\/p><\/div>\n\t\t\t\t<div class=\"wp-block-group aa-tp-dx__step is-layout-flow wp-block-group-is-layout-flow\"><p class=\"aa-tp-dx__step-num wp-block-paragraph\">02<\/p><h4 class=\"wp-block-heading\">Typer les d\u00e9p\u00f4ts<\/h4><p class=\"wp-block-paragraph\">Les d\u00e9p\u00f4ts sont ensuite typ\u00e9s, pour \u00e9tablir que la substance amylo\u00efde est bien faite de prot\u00e9ine SAA et non d\u2019un autre pr\u00e9curseur.<\/p><\/div>\n\t\t\t\t<div class=\"wp-block-group aa-tp-dx__step is-layout-flow wp-block-group-is-layout-flow\"><p class=\"aa-tp-dx__step-num wp-block-paragraph\">03<\/p><h4 class=\"wp-block-heading\">Mesurer l\u2019inflammation<\/h4><p class=\"wp-block-paragraph\">On dose la SAA circulante et la prot\u00e9ine C-r\u00e9active (CRP). Les anciens r\u00e9sultats de CRP sont aussi examin\u00e9s\u00a0: ils r\u00e9v\u00e8lent depuis combien de temps dure l\u2019inflammation.<\/p><\/div>\n\t\t\t\t<div class=\"wp-block-group aa-tp-dx__step is-layout-flow wp-block-group-is-layout-flow\"><p class=\"aa-tp-dx__step-num wp-block-paragraph\">04<\/p><h4 class=\"wp-block-heading\">\u00c9valuer les organes<\/h4><p class=\"wp-block-paragraph\">Des analyses de sang et d\u2019urine mesurent la fonction r\u00e9nale, et le c\u0153ur est \u00e9galement examin\u00e9. Ensemble, elles montrent jusqu\u2019o\u00f9 les d\u00e9p\u00f4ts ont progress\u00e9.<\/p><\/div>\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-dx__photo is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-pipette-filling-a-laboratory-sample-vial-1024x683.jpg\" alt=\"Une pipette remplissant un flacon d&#x2019;&#xE9;chantillon de laboratoire\" class=\"wp-image-704\" srcset=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-pipette-filling-a-laboratory-sample-vial-1024x683.jpg 1024w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-pipette-filling-a-laboratory-sample-vial-300x200.jpg 300w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-pipette-filling-a-laboratory-sample-vial-768x512.jpg 768w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-pipette-filling-a-laboratory-sample-vial-1536x1024.jpg 1536w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<section class=\"wp-block-group aa-section aa-section--cream aa-treating is-layout-flow wp-block-group-is-layout-flow\" id=\"treatment\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group aa-centered-head is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">06<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">Traitement<\/h2>\n\t\t\t<div class=\"aa-divider-dot\"><\/div>\n\t\t\t<p class=\"wp-block-paragraph\">Le traitement vise \u00e0 contr\u00f4ler la maladie inflammatoire ou infectieuse sous-jacente et \u00e0 r\u00e9duire la production de prot\u00e9ine amylo\u00efde A s\u00e9rique (SAA), la prot\u00e9ine pr\u00e9curseur qui forme les d\u00e9p\u00f4ts amylo\u00efdes AA.<\/p>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-treat-lead is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-tp-treat-lead__photo is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"745\" src=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/medicine-vials-and-ampoules-1024x745.jpg\" alt=\"Des flacons et des ampoules de m&#xE9;dicaments\" class=\"wp-image-705\" srcset=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/medicine-vials-and-ampoules-1024x745.jpg 1024w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/medicine-vials-and-ampoules-300x218.jpg 300w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/medicine-vials-and-ampoules-768x559.jpg 768w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/medicine-vials-and-ampoules-1536x1117.jpg 1536w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-tp-treat-lead__body is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<h3 class=\"wp-block-heading\">Traiter la cause, pas les d\u00e9p\u00f4ts<\/h3>\n\t\t\t\t<p class=\"wp-block-paragraph\">L\u2019objectif est de r\u00e9duire l\u2019exc\u00e8s de SAA mal repli\u00e9e en emp\u00eachant le foie de la surproduire. Il n\u2019existe qu\u2019un moyen d\u2019y parvenir\u00a0: contr\u00f4ler la maladie inflammatoire sous-jacente.<\/p>\n\t\t\t\t<p class=\"wp-block-paragraph\">Il faut le dire clairement\u00a0: aucun traitement ne permet aujourd\u2019hui d\u2019\u00e9liminer les fibrilles amylo\u00efdes une fois form\u00e9es. Ce qui est d\u00e9j\u00e0 d\u00e9pos\u00e9 reste. C\u2019est pr\u00e9cis\u00e9ment pourquoi agir t\u00f4t, et d\u00e9pister les personnes \u00e0 risque, change l\u2019\u00e9volution de la maladie.<\/p>\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-treating-grid is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<div class=\"wp-block-group aa-treating-card is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-icon-tile\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M10.5 20.5 3.5 13.5a5 5 0 0 1 7-7l7 7a5 5 0 0 1-7 7Z\"><\/path><path d=\"m8.5 8.5 7 7\"><\/path><\/svg><\/span><h3 class=\"wp-block-heading\">Fi\u00e8vre m\u00e9diterran\u00e9enne familiale<\/h3><p class=\"wp-block-paragraph\">Un anti-inflammatoire quotidien, pris \u00e0 vie. Il supprime les pouss\u00e9es inflammatoires r\u00e9p\u00e9t\u00e9es et, avec elles, l\u2019augmentation de la SAA.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-treating-card is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-icon-tile\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M12 22s8-4 8-10V5l-8-3-8 3v7c0 6 8 10 8 10z\"><\/path><\/svg><\/span><h3 class=\"wp-block-heading\">Infections chroniques<\/h3><p class=\"wp-block-paragraph\">Des antibiotiques, pour \u00e9liminer l\u2019infection qui entretenait la r\u00e9ponse inflammatoire.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-treating-card is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-icon-tile\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><circle cx=\"12\" cy=\"12\" r=\"10\"><\/circle><circle cx=\"12\" cy=\"12\" r=\"6\"><\/circle><circle cx=\"12\" cy=\"12\" r=\"2\"><\/circle><\/svg><\/span><h3 class=\"wp-block-heading\">Maladie inflammatoire<\/h3><p class=\"wp-block-paragraph\">Des cortico\u00efdes ou des bioth\u00e9rapies, choisis selon la maladie et sa r\u00e9ponse au traitement.<\/p><\/div>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-support is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<h4 class=\"wp-block-heading\">Quand les reins l\u00e2chent<\/h4>\n\t\t\t<p class=\"wp-block-paragraph\">En cas d\u2019insuffisance r\u00e9nale terminale, une greffe est possible chez les patients par ailleurs en bonne sant\u00e9. Une dialyse peut \u00eatre n\u00e9cessaire dans l\u2019intervalle. Aucune des deux n\u2019\u00e9limine la substance amylo\u00efde, mais toutes deux donnent le temps n\u00e9cessaire au contr\u00f4le de l\u2019inflammation.<\/p>\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<section class=\"wp-block-group aa-section aa-section--forest aa-tp-outlook is-layout-flow wp-block-group-is-layout-flow\" id=\"follow-up\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-outlook__photo is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/two-people-holding-hands-1024x683.jpg\" alt=\"Deux personnes se tenant la main\" class=\"wp-image-706\" srcset=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/two-people-holding-hands-1024x683.jpg 1024w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/two-people-holding-hands-300x200.jpg 300w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/two-people-holding-hands-768x512.jpg 768w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/two-people-holding-hands-1536x1024.jpg 1536w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-outlook__body is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">07<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">Pr\u00e9vention et suivi<\/h2>\n\t\t\t<h4 class=\"wp-block-heading\">D\u00e9pistage<\/h4>\n\t\t\t<p class=\"wp-block-paragraph\">La pr\u00e9vention compte surtout pour les personnes qui vivent depuis l\u2019enfance avec une maladie auto-inflammatoire g\u00e9n\u00e9tique. Elles ont besoin d\u2019un traitement anti-inflammatoire \u00e0 vie, et d\u2019un contr\u00f4le une fois par an pour rep\u00e9rer une amylose avant qu\u2019elle n\u2019ait caus\u00e9 de d\u00e9g\u00e2ts.<\/p>\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-aa-screening is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<p class=\"aa-aa-screening__label wp-block-paragraph\">Une fois par an<\/p>\n\t\t\t\t\n\t\t\t\t<div class=\"wp-block-group aa-aa-screening__items is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t\t<p class=\"aa-aa-screening__item wp-block-paragraph\">Une analyse d\u2019urine, pour rechercher une fuite de prot\u00e9ines par les reins<\/p>\n\t\t\t\t\t<p class=\"aa-aa-screening__item wp-block-paragraph\">Une prise de sang, pour mesurer l\u2019inflammation et la fonction r\u00e9nale<\/p>\n\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t\t<h4 class=\"wp-block-heading\">Un suivi partag\u00e9<\/h4>\n\t\t\t<p class=\"wp-block-paragraph\">Une fois l\u2019amylose AA confirm\u00e9e, le suivi est \u00e9troit et associe plusieurs intervenants\u00a0: le m\u00e9decin qui traite la maladie inflammatoire sous-jacente, votre m\u00e9decin traitant, et un sp\u00e9cialiste de l\u2019amylose AA. Chacun voit une partie diff\u00e9rente du tableau.<\/p>\n\t\t\t<p class=\"aa-tp-outlook__closing wp-block-paragraph\">Certains cas d\u2019amylose AA peuvent \u00eatre \u00e9vit\u00e9s gr\u00e2ce \u00e0 un contr\u00f4le pr\u00e9coce et durable de la maladie inflammatoire ou infectieuse sous-jacente. C\u2019est ce qui rend le contr\u00f4le annuel utile.<\/p>\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<section class=\"wp-block-group aa-section aa-section--white aa-tp-faq is-layout-flow wp-block-group-is-layout-flow\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group aa-centered-head is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">FAQ<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">Questions fr\u00e9quentes<\/h2>\n\t\t\t<div class=\"aa-divider-dot\"><\/div>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-acc is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\n\t\t\t<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>L\u2019amylose AA est-elle h\u00e9r\u00e9ditaire\u202f?<\/summary>\n\t\t\t<p class=\"wp-block-paragraph\">L\u2019amylose AA elle-m\u00eame n\u2019est pas h\u00e9r\u00e9ditaire, mais certaines des maladies qui la provoquent le sont. La fi\u00e8vre m\u00e9diterran\u00e9enne familiale, le CAPS, le MKD et le TRAPS sont des maladies auto-inflammatoires g\u00e9n\u00e9tiques, qui peuvent se transmettre dans les familles. Si l\u2019une d\u2019elles a \u00e9t\u00e9 diagnostiqu\u00e9e dans votre famille, demandez \u00e0 votre m\u00e9decin si vos proches doivent \u00eatre examin\u00e9s.<\/p>\n\t\t\t<\/details>\n\t\t\t\n\t\t\t\n\t\t\t<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>Peut-on pr\u00e9venir l\u2019amylose AA\u202f?<\/summary>\n\t\t\t<p class=\"wp-block-paragraph\">Dans une large mesure, oui, et c\u2019est ce qui distingue l\u2019amylose AA des autres formes. Contr\u00f4ler l\u2019inflammation sous-jacente maintient les taux de SAA bas, et sans exc\u00e8s de SAA, il n\u2019y a pas de mati\u00e8re premi\u00e8re pour la substance amylo\u00efde. Pour les personnes atteintes d\u2019une maladie auto-inflammatoire g\u00e9n\u00e9tique, la pr\u00e9vention, en pratique, c\u2019est un traitement \u00e0 vie et un contr\u00f4le annuel.<\/p>\n\t\t\t<\/details>\n\t\t\t\n\t\t\t\n\t\t\t<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>Le traitement \u00e9limine-t-il les d\u00e9p\u00f4ts\u202f?<\/summary>\n\t\t\t<p class=\"wp-block-paragraph\">Non. Aucun traitement disponible aujourd\u2019hui n\u2019\u00e9limine les fibrilles amylo\u00efdes d\u00e9j\u00e0 form\u00e9es. Le traitement emp\u00eache la formation de nouvelles fibrilles, ce qui permet aux organes de se stabiliser et, dans certains cas, de retrouver une partie de leur fonction. Ce qui est d\u00e9j\u00e0 d\u00e9pos\u00e9 reste.<\/p>\n\t\t\t<\/details>\n\t\t\t\n\t\t\t\n\t\t\t<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>L\u2019amylose AA touche-t-elle le c\u0153ur\u202f?<\/summary>\n\t\t\t<p class=\"wp-block-paragraph\">Des d\u00e9p\u00f4ts peuvent \u00eatre pr\u00e9sents dans le c\u0153ur mais, contrairement \u00e0 l\u2019amylose AL, les signes d\u2019insuffisance cardiaque sont g\u00e9n\u00e9ralement absents. Dans l\u2019amylose AA, ce sont les reins, et non le c\u0153ur, qui dominent le tableau clinique.<\/p>\n\t\t\t<\/details>\n\t\t\t\n\t\t\t\n\t\t\t<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>Qu\u2019est-ce que la SAA\u202f?<\/summary>\n\t\t\t<p class=\"wp-block-paragraph\">La prot\u00e9ine amylo\u00efde A s\u00e9rique est une prot\u00e9ine fabriqu\u00e9e par le foie. Elle circule dans le sang \u00e0 faible concentration, et sa production augmente dans le cadre de la r\u00e9ponse normale de l\u2019organisme \u00e0 l\u2019inflammation. Dans l\u2019amylose AA, une inflammation qui ne s\u2019\u00e9teint jamais maintient la SAA \u00e9lev\u00e9e pendant des ann\u00e9es, jusqu\u2019\u00e0 ce qu\u2019une partie se replie mal et forme des d\u00e9p\u00f4ts.<\/p>\n\t\t\t<\/details>\n\t\t\t\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-disclaimer is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"wp-block-paragraph\">Cette page est une information g\u00e9n\u00e9rale destin\u00e9e aux patients, aux familles et aux professionnels de sant\u00e9. Elle ne remplace pas un avis m\u00e9dical. Parlez toujours de votre situation avec votre \u00e9quipe sp\u00e9cialis\u00e9e.<\/p>\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<section class=\"wp-block-group aa-next aa-next--split is-layout-flow wp-block-group-is-layout-flow\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group aa-next__head is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">Continuer<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">Autres types<\/h2>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-next__grid is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<div class=\"wp-block-group aa-next-card is-layout-flow wp-block-group-is-layout-flow\"><h3 class=\"wp-block-heading\"><a href=\"https:\/\/www.amyloidosisalliance.org\/fr\/types-damylose\/amylose-al\/\">Amylose AL<\/a><\/h3><p class=\"wp-block-paragraph\">La forme syst\u00e9mique la plus fr\u00e9quente, due aux cha\u00eenes l\u00e9g\u00e8res produites dans la moelle osseuse.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-next-card is-layout-flow wp-block-group-is-layout-flow\"><h3 class=\"wp-block-heading\"><a href=\"https:\/\/www.amyloidosisalliance.org\/fr\/types-damylose\/amylose-attr\/\">Amylose ATTR<\/a><\/h3><p class=\"wp-block-paragraph\">Due \u00e0 la transthyr\u00e9tine, h\u00e9r\u00e9ditaire dans l\u2019ATTRv, li\u00e9e \u00e0 l\u2019\u00e2ge dans l\u2019ATTRwt.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-next-card is-layout-flow wp-block-group-is-layout-flow\"><h3 class=\"wp-block-heading\"><a href=\"https:\/\/www.amyloidosisalliance.org\/fr\/types-damylose\/autres-types\/\">Autres types<\/a><\/h3><p class=\"wp-block-paragraph\">Les formes h\u00e9r\u00e9ditaires rares, et l\u2019amylose localis\u00e9e, limit\u00e9e \u00e0 un seul site.<\/p><\/div>\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n","protected":false},"excerpt":{"rendered":"<p>Accueil\u203aAmylose\u203aTypes d\u2019amylose\u203aAmylose AA Types d\u2019amylose Amylose AA L\u2019amylose AA est une complication d\u2019une inflammation de longue dur\u00e9e. Elle n\u2019est pas h\u00e9r\u00e9ditaire, et ce n\u2019est pas un cancer du sang\u00a0: elle se d\u00e9veloppe lorsqu\u2019une autre maladie entretient une inflammation dans l\u2019organisme pendant des ann\u00e9es. C\u2019est en contr\u00f4lant cette maladie qu\u2019on l\u2019arr\u00eate, ce qui fait de l\u2019amylose [&hellip;]<\/p>\n","protected":false},"author":0,"featured_media":0,"parent":1427,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1419","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Amylose AA\u00a0: causes, sympt\u00f4mes et traitement<\/title>\n<meta name=\"description\" content=\"L\u2019amylose AA survient apr\u00e8s des ann\u00e9es d\u2019inflammation non trait\u00e9e. 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