{"id":1407,"date":"2026-07-10T16:36:42","date_gmt":"2026-07-10T14:36:42","guid":{"rendered":"https:\/\/amyloidosisalliance.local\/autres-types\/"},"modified":"2026-09-29T11:03:50","modified_gmt":"2026-09-29T09:03:50","slug":"autres-types","status":"publish","type":"page","link":"https:\/\/www.amyloidosisalliance.org\/fr\/types-damylose\/autres-types\/","title":{"rendered":"Autres types"},"content":{"rendered":"\n<nav class=\"wp-block-group aa-breadcrumb is-layout-flow wp-block-group-is-layout-flow\" aria-label=\"Breadcrumb\">\n\t\n\t<div class=\"aa-inner\"><a href=\"\/\">Accueil<\/a><span class=\"aa-breadcrumb__sep\">\u203a<\/span><span class=\"aa-breadcrumb__label\">Amylose<\/span><span class=\"aa-breadcrumb__sep\">\u203a<\/span><a href=\"https:\/\/www.amyloidosisalliance.org\/fr\/types-damylose\/\">Types d\u2019amylose<\/a><span class=\"aa-breadcrumb__sep\">\u203a<\/span><span class=\"aa-breadcrumb__current\">Autres types<\/span><\/div>\n\t\n<\/nav>\n\n<section class=\"wp-block-group aa-page-hero is-layout-flow wp-block-group-is-layout-flow\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group aa-page-hero__grid is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\n\t\t\t<div class=\"wp-block-group is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<p class=\"aa-overline wp-block-paragraph\">Types d\u2019amylose<\/p>\n\t\t\t\t<h1 class=\"wp-block-heading\">Autres types<\/h1>\n\t\t\t\t<p class=\"aa-lead wp-block-paragraph\">Les amyloses AL, AA et ATTR sont les formes syst\u00e9miques d\u2019amylose les plus couramment reconnues. Les autres formes comprennent les amyloses h\u00e9r\u00e9ditaires rares et l\u2019amylose localis\u00e9e. Deux situations sortent de ce cadre\u00a0: des prot\u00e9ines h\u00e9r\u00e9ditaires autres que la transthyr\u00e9tine, et des d\u00e9p\u00f4ts qui ne quittent jamais l\u2019organe o\u00f9 ils se sont form\u00e9s. Elles ont peu de points communs, sinon d\u2019\u00eatre toutes deux des exceptions, et de reposer toutes deux sur un diagnostic pr\u00e9cis.<\/p>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-page-hero__photo is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/the-objective-lens-of-a-microscope-above-a-slide-1024x683.jpg\" alt=\"L&#x2019;objectif d&#x2019;un microscope au-dessus d&#x2019;une lame\" class=\"wp-image-679\" srcset=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/the-objective-lens-of-a-microscope-above-a-slide-1024x683.jpg 1024w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/the-objective-lens-of-a-microscope-above-a-slide-300x200.jpg 300w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/the-objective-lens-of-a-microscope-above-a-slide-768x512.jpg 768w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/the-objective-lens-of-a-microscope-above-a-slide-1536x1024.jpg 1536w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<section class=\"wp-block-group aa-section aa-section--white aa-what is-layout-flow wp-block-group-is-layout-flow\" id=\"what\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">01<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">Les exceptions<\/h2>\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-key-idea is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<p class=\"aa-key-idea__label wp-block-paragraph\">\u00c0 retenir<\/p>\n\t\t\t\t<p class=\"wp-block-paragraph\">Les deux sont rares, et aucune ne peut \u00eatre reconnue sur les seuls sympt\u00f4mes. Dans les deux cas, c\u2019est en identifiant pr\u00e9cis\u00e9ment ce qui s\u2019est d\u00e9pos\u00e9, et o\u00f9, que le traitement devient possible.<\/p>\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-what-cols is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-what-col is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<h4 class=\"wp-block-heading\">Au-del\u00e0 des formes courantes<\/h4>\n\t\t\t\t<p class=\"wp-block-paragraph\">Les amyloses AL, AA et \u00e0 TTR repr\u00e9sentent la grande majorit\u00e9 des amyloses, et chacune a sa propre page. Restent des formes si rares que la plupart des m\u00e9decins n\u2019en verront jamais.<\/p>\n\t\t\t\t<p class=\"wp-block-paragraph\">Cette raret\u00e9 est en soi la difficult\u00e9. Aucune des deux formes d\u00e9crites ici ne s\u2019annonce\u202f; toutes deux sont g\u00e9n\u00e9ralement d\u00e9couvertes alors que l\u2019on cherchait tout autre chose.<\/p>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-what-col is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<h4 class=\"wp-block-heading\">Pourquoi elles sont r\u00e9unies ici<\/h4>\n\t\t\t\t<p class=\"wp-block-paragraph\">Pas parce qu\u2019elles se ressemblent\u00a0: ce n\u2019est pas le cas. L\u2019une est h\u00e9r\u00e9ditaire et s\u2019attaque aux reins\u202f; l\u2019autre est acquise et reste dans un seul organe.<\/p>\n\t\t\t\t<p class=\"wp-block-paragraph\">Elles sont r\u00e9unies parce que chacune sort de la description habituelle d\u2019une amylose, et parce que dans les deux cas, c\u2019est le laboratoire, et non l\u2019examen clinique, qui a le dernier mot.<\/p>\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<section class=\"wp-block-group aa-section aa-section--cream aa-tp-duo-sec is-layout-flow wp-block-group-is-layout-flow\" id=\"forms\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group aa-centered-head is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">02<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">Deux exceptions<\/h2>\n\t\t\t<div class=\"aa-divider-dot\"><\/div>\n\t\t\t<p class=\"wp-block-paragraph\">L\u2019une est une question de prot\u00e9ine. L\u2019autre, une question de distance parcourue.<\/p>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-duo is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-tp-duo__card is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<p class=\"aa-tp-duo__tag wp-block-paragraph\">H\u00c9R\u00c9DITAIRES RARES<\/p>\n\t\t\t\t<h3 class=\"wp-block-heading\">Des prot\u00e9ines h\u00e9r\u00e9ditaires autres que la TTR<\/h3>\n\t\t\t\t<p class=\"wp-block-paragraph\">Des mutations de la cha\u00eene alpha du fibrinog\u00e8ne, des apolipoprot\u00e9ines, du lysozyme ou de la gelsoline. Toutes se transmettent sur le mode autosomique dominant, et les reins sont la cible principale.<\/p>\n\t\t\t\t<p class=\"wp-block-paragraph\">Les sympt\u00f4mes peuvent \u00eatre identiques d\u2019une forme \u00e0 l\u2019autre, alors que les traitements n\u2019ont rien en commun.<\/p>\n\t\t\t\t\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\"><div class=\"wp-block-button aa-btn aa-btn--teal\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.amyloidosisalliance.org\/fr\/types-damylose\/amyloses-hereditaires-rares\/\">Formes h\u00e9r\u00e9ditaires rares \u2192<\/a><\/div><\/div>\n\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-tp-duo__card is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<p class=\"aa-tp-duo__tag wp-block-paragraph\">LOCALIS\u00c9E<\/p>\n\t\t\t\t<h3 class=\"wp-block-heading\">Des d\u00e9p\u00f4ts limit\u00e9s \u00e0 un seul organe<\/h3>\n\t\t\t\t<p class=\"wp-block-paragraph\">Le plus souvent une substance amylo\u00efde de type AL, faite des m\u00eames cha\u00eenes l\u00e9g\u00e8res que dans la maladie syst\u00e9mique, mais produites par des plasmocytes situ\u00e9s dans l\u2019organe lui-m\u00eame. Rien ne passe dans la circulation sanguine, donc rien ne se d\u00e9pose ailleurs.<\/p>\n\t\t\t\t<p class=\"wp-block-paragraph\">Les voies respiratoires et la vessie sont les localisations les plus fr\u00e9quentes, et le traitement est local.<\/p>\n\t\t\t\t\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\"><div class=\"wp-block-button aa-btn aa-btn--teal\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.amyloidosisalliance.org\/fr\/types-damylose\/amylose-localisee\/\">Amylose localis\u00e9e \u2192<\/a><\/div><\/div>\n\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-note is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"wp-block-paragraph\">Dans les deux cas, la biopsie est souvent r\u00e9alis\u00e9e pour \u00e9carter autre chose, et la substance amylo\u00efde est d\u00e9couverte par surprise. Ce qui suit (le typage de la prot\u00e9ine, l\u2019\u00e9valuation de son extension) est ce qui d\u00e9cide du traitement.<\/p>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-disclaimer is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"wp-block-paragraph\">Cette page est une information g\u00e9n\u00e9rale destin\u00e9e aux patients, aux familles et aux professionnels de sant\u00e9. Elle ne remplace pas un avis m\u00e9dical. Parlez toujours de votre situation avec votre \u00e9quipe sp\u00e9cialis\u00e9e.<\/p>\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<section class=\"wp-block-group aa-next aa-next--split is-layout-flow wp-block-group-is-layout-flow\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group aa-next__head is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">Continuer<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">Les formes courantes<\/h2>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-next__grid is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<div class=\"wp-block-group aa-next-card is-layout-flow wp-block-group-is-layout-flow\"><h3 class=\"wp-block-heading\"><a href=\"https:\/\/www.amyloidosisalliance.org\/fr\/types-damylose\/amylose-al\/\">Amylose AL<\/a><\/h3><p class=\"wp-block-paragraph\">La forme syst\u00e9mique la plus fr\u00e9quente, due aux cha\u00eenes l\u00e9g\u00e8res produites dans la moelle osseuse.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-next-card is-layout-flow wp-block-group-is-layout-flow\"><h3 class=\"wp-block-heading\"><a href=\"https:\/\/www.amyloidosisalliance.org\/fr\/types-damylose\/amylose-aa\/\">Amylose AA<\/a><\/h3><p class=\"wp-block-paragraph\">Une complication d\u2019une inflammation de longue dur\u00e9e, qui touche avant tout les reins.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-next-card is-layout-flow wp-block-group-is-layout-flow\"><h3 class=\"wp-block-heading\"><a href=\"https:\/\/www.amyloidosisalliance.org\/fr\/types-damylose\/amylose-attr\/\">Amylose ATTR<\/a><\/h3><p class=\"wp-block-paragraph\">Due \u00e0 la transthyr\u00e9tine, h\u00e9r\u00e9ditaire dans l\u2019ATTRv, li\u00e9e \u00e0 l\u2019\u00e2ge dans l\u2019ATTRwt.<\/p><\/div>\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n","protected":false},"excerpt":{"rendered":"<p>Accueil\u203aAmylose\u203aTypes d\u2019amylose\u203aAutres types Types d\u2019amylose Autres types Les amyloses AL, AA et ATTR sont les formes syst\u00e9miques d\u2019amylose les plus couramment reconnues. Les autres formes comprennent les amyloses h\u00e9r\u00e9ditaires rares et l\u2019amylose localis\u00e9e. Deux situations sortent de ce cadre\u00a0: des prot\u00e9ines h\u00e9r\u00e9ditaires autres que la transthyr\u00e9tine, et des d\u00e9p\u00f4ts qui ne quittent jamais l\u2019organe o\u00f9 [&hellip;]<\/p>\n","protected":false},"author":0,"featured_media":0,"parent":1427,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1407","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Les autres types d\u2019amylose, au-del\u00e0 des formes AL, AA et ATTR<\/title>\n<meta name=\"description\" content=\"Les amyloses AL, AA et ATTR sont les formes syst\u00e9miques les plus connues. Deux autres situations sortent de ce cadre\u00a0: des prot\u00e9ines h\u00e9r\u00e9ditaires rares, et une substance amylo\u00efde limit\u00e9e \u00e0 un seul organe.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.amyloidosisalliance.org\/fr\/types-damylose\/autres-types\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Les autres types d\u2019amylose, au-del\u00e0 des formes AL, AA et ATTR\" \/>\n<meta property=\"og:description\" content=\"Les amyloses AL, AA et ATTR sont les formes syst\u00e9miques les plus connues. 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