{"id":2469,"date":"2026-07-10T14:54:26","date_gmt":"2026-07-10T12:54:26","guid":{"rendered":"https:\/\/www.amyloidosisalliance.org\/amiloidosis-aa\/"},"modified":"2026-10-22T15:23:19","modified_gmt":"2026-10-22T13:23:19","slug":"amiloidosis-aa","status":"publish","type":"page","link":"https:\/\/www.amyloidosisalliance.org\/es\/tipos-de-amiloidosis\/amiloidosis-aa\/","title":{"rendered":"Amiloidosis AA"},"content":{"rendered":"\n<nav class=\"wp-block-group aa-breadcrumb aa-events-hero__crumb is-layout-flow wp-block-group-is-layout-flow\" aria-label=\"Breadcrumb\">\n\t\n\t<div class=\"aa-inner\"><a href=\"\/\">Inicio<\/a><span class=\"aa-breadcrumb__sep\">\u203a<\/span><span class=\"aa-breadcrumb__label\">Amiloidosis<\/span><span class=\"aa-breadcrumb__sep\">\u203a<\/span><a href=\"https:\/\/www.amyloidosisalliance.org\/types-of-amyloidosis\/\">Tipos de amiloidosis<\/a><span class=\"aa-breadcrumb__sep\">\u203a<\/span><span class=\"aa-breadcrumb__current\">Amiloidosis AA<\/span><\/div>\n\t\n<\/nav>\n\n<section class=\"wp-block-group aa-events-hero aa-events-hero--art aa-events-hero--aa is-layout-flow wp-block-group-is-layout-flow\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t<p class=\"aa-events-hero__kicker wp-block-paragraph\">Tipos de amiloidosis<\/p>\n\t\t<h1 class=\"wp-block-heading\">Amiloidosis AA<\/h1>\n\t\t<p class=\"wp-block-paragraph\">La amiloidosis AA es una complicaci\u00f3n de una inflamaci\u00f3n de larga duraci\u00f3n. No es hereditaria ni es un c\u00e1ncer de la sangre: se desarrolla cuando otra enfermedad mantiene el organismo inflamado durante a\u00f1os. Controlar esa enfermedad es lo que la detiene, lo que convierte a la amiloidosis AA en la \u00fanica forma de amiloidosis que realmente se puede prevenir.<\/p>\n\t<\/div>\n\t\n\t\n\t<div class=\"wp-block-group aa-events-hero__art is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<figure class=\"wp-block-image size-full\"><img decoding=\"async\" src=\"\/wp-content\/themes\/amyloidosis-alliance\/assets\/images\/disease\/aa.svg\" alt=\"Esquema: una inflamaci&#xF3;n cr&#xF3;nica produce una prote&#xED;na que se pliega mal, se alinea y se apila formando una fibrilla amiloide\"\/><\/figure>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<nav class=\"wp-block-group aa-anchorband is-layout-flow wp-block-group-is-layout-flow\" aria-label=\"Section navigation\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-columns aa-anchor-cols is-layout-flex wp-container-core-columns-is-layout-b2e659ba wp-block-columns-is-layout-flex\">\n\t\t\t<div class=\"wp-block-column aa-anchor-item is-layout-flow wp-block-column-is-layout-flow\"><p class=\"num wp-block-paragraph\">01<\/p><p class=\"lbl wp-block-paragraph\"><a href=\"#what\">\u00bfQu\u00e9 es la AA?<\/a><\/p><\/div>\n\t\t\t<div class=\"wp-block-column aa-anchor-item is-layout-flow wp-block-column-is-layout-flow\"><p class=\"num wp-block-paragraph\">02<\/p><p class=\"lbl wp-block-paragraph\"><a href=\"#causes\">C\u00f3mo se desarrolla<\/a><\/p><\/div>\n\t\t\t<div class=\"wp-block-column aa-anchor-item is-layout-flow wp-block-column-is-layout-flow\"><p class=\"num wp-block-paragraph\">03<\/p><p class=\"lbl wp-block-paragraph\"><a href=\"#conditions\">Causas subyacentes<\/a><\/p><\/div>\n\t\t\t<div class=\"wp-block-column aa-anchor-item is-layout-flow wp-block-column-is-layout-flow\"><p class=\"num wp-block-paragraph\">04<\/p><p class=\"lbl wp-block-paragraph\"><a href=\"#symptoms\">S\u00edntomas<\/a><\/p><\/div>\n\t\t\t<div class=\"wp-block-column aa-anchor-item is-layout-flow wp-block-column-is-layout-flow\"><p class=\"num wp-block-paragraph\">05<\/p><p class=\"lbl wp-block-paragraph\"><a href=\"#diagnosis\">Diagn\u00f3stico<\/a><\/p><\/div>\n\t\t\t<div class=\"wp-block-column aa-anchor-item is-layout-flow wp-block-column-is-layout-flow\"><p class=\"num wp-block-paragraph\">06<\/p><p class=\"lbl wp-block-paragraph\"><a href=\"#treatment\">Tratamiento<\/a><\/p><\/div>\n\t\t\t<div class=\"wp-block-column aa-anchor-item is-layout-flow wp-block-column-is-layout-flow\"><p class=\"num wp-block-paragraph\">07<\/p><p class=\"lbl wp-block-paragraph\"><a href=\"#follow-up\">Prevenci\u00f3n<\/a><\/p><\/div>\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/nav>\n\n<section class=\"wp-block-group aa-section aa-section--white aa-what is-layout-flow wp-block-group-is-layout-flow\" id=\"what\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">01<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">\u00bfQu\u00e9 es la amiloidosis AA?<\/h2>\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-key-idea is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<p class=\"aa-key-idea__label wp-block-paragraph\">Idea clave<\/p>\n\t\t\t\t<p class=\"wp-block-paragraph\">La amiloidosis AA es una complicaci\u00f3n poco frecuente de una inflamaci\u00f3n persistente, causada la mayor\u00eda de las veces por una enfermedad inflamatoria o infecciosa cr\u00f3nica. Si se localiza la inflamaci\u00f3n y se trata, se detiene el amiloide en su origen.<\/p>\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-what-cols is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-what-col is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<h4 class=\"wp-block-heading\">Una prote\u00edna de la inflamaci\u00f3n<\/h4>\n\t\t\t\t<p class=\"wp-block-paragraph\">El amiloide de la amiloidosis AA est\u00e1 formado por <strong>prote\u00edna amiloide A s\u00e9rica<\/strong> (SAA), una prote\u00edna producida por el h\u00edgado. Normalmente est\u00e1 presente en la sangre en concentraciones bajas, y su producci\u00f3n aumenta de forma marcada cada vez que el organismo sufre una inflamaci\u00f3n.<\/p>\n\t\t\t\t<p class=\"wp-block-paragraph\">Esta reacci\u00f3n es totalmente normal, e inofensiva, siempre que sea breve. El problema empieza cuando la inflamaci\u00f3n dura a\u00f1os en lugar de semanas. La SAA circula entonces en exceso, se pliega mal y se apila formando fibrillas amiloides insolubles.<\/p>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-what-col is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<h4 class=\"wp-block-heading\">Los \u00f3rganos que afecta<\/h4>\n\t\t\t\t<p class=\"wp-block-paragraph\">Los <strong>ri\u00f1ones<\/strong>, ante todo: se ven afectados en la gran mayor\u00eda de los pacientes, y suele ser un problema renal lo que conduce al diagn\u00f3stico.<\/p>\n\t\t\t\t<p class=\"wp-block-paragraph\">Los dep\u00f3sitos tambi\u00e9n alcanzan el tubo digestivo (est\u00f3mago e intestinos), as\u00ed como el h\u00edgado y las gl\u00e1ndulas salivales. Cualquier enfermedad capaz de mantener el organismo inflamado a largo plazo puede, en principio, provocar una amiloidosis AA.<\/p>\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<section class=\"wp-block-group aa-section aa-section--cream aa-forms is-layout-flow wp-block-group-is-layout-flow\" id=\"causes\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group aa-centered-head is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">02<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">C\u00f3mo se desarrolla la amiloidosis AA<\/h2>\n\t\t\t<div class=\"aa-divider-dot\"><\/div>\n\t\t\t<p class=\"wp-block-paragraph\">Cuatro etapas que convierten una respuesta inmunitaria corriente en una enfermedad de los \u00f3rganos.<\/p>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-proc-grid is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<div class=\"wp-block-group aa-proc-step is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-proc-step__icon\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M8.5 14.5A2.5 2.5 0 0 0 11 12c0-1.38-.5-2-1-3-1.07-2.14-.22-4.05 2-6 .5 2.5 2 4.9 4 6.5 2 1.6 3 3.5 3 5.5a7 7 0 1 1-14 0c0-1.15.43-2.29 1-3a2.5 2.5 0 0 0 2.5 2.5z\"><\/path><\/svg><\/span><p class=\"aa-proc-step__num wp-block-paragraph\">Paso 01<\/p><h4 class=\"wp-block-heading\">Inflamaci\u00f3n cr\u00f3nica<\/h4><p class=\"wp-block-paragraph\">Otra enfermedad mantiene el organismo inflamado: una infecci\u00f3n de larga duraci\u00f3n, una artritis inflamatoria, una enfermedad intestinal, un s\u00edndrome autoinflamatorio.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-proc-step is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-proc-step__icon\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><polyline points=\"22 7 13.5 15.5 8.5 10.5 2 17\"><\/polyline><polyline points=\"16 7 22 7 22 13\"><\/polyline><\/svg><\/span><p class=\"aa-proc-step__num wp-block-paragraph\">Paso 02<\/p><h4 class=\"wp-block-heading\">El h\u00edgado produce SAA<\/h4><p class=\"wp-block-paragraph\">En respuesta, el h\u00edgado aumenta su producci\u00f3n de prote\u00edna amiloide A s\u00e9rica. Los niveles en sangre se mantienen elevados, no durante d\u00edas, sino durante a\u00f1os.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-proc-step is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-proc-step__icon\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><polyline points=\"16 3 21 3 21 8\"><\/polyline><line x1=\"4\" y1=\"20\" x2=\"21\" y2=\"3\"><\/line><polyline points=\"21 16 21 21 16 21\"><\/polyline><line x1=\"15\" y1=\"15\" x2=\"21\" y2=\"21\"><\/line><line x1=\"4\" y1=\"4\" x2=\"9\" y2=\"9\"><\/line><\/svg><\/span><p class=\"aa-proc-step__num wp-block-paragraph\">Paso 03<\/p><h4 class=\"wp-block-heading\">Se forman fibrillas<\/h4><p class=\"wp-block-paragraph\">Al circular en exceso, la SAA se pliega mal y se apila formando fibrillas amiloides insolubles que el organismo no puede eliminar.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-proc-step is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-proc-step__icon\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M10.29 3.86L1.82 18a2 2 0 0 0 1.71 3h16.94a2 2 0 0 0 1.71-3L13.71 3.86a2 2 0 0 0-3.42 0z\"><\/path><line x1=\"12\" y1=\"9\" x2=\"12\" y2=\"13\"><\/line><line x1=\"12\" y1=\"17\" x2=\"12.01\" y2=\"17\"><\/line><\/svg><\/span><p class=\"aa-proc-step__num wp-block-paragraph\">Paso 04<\/p><h4 class=\"wp-block-heading\">Dep\u00f3sitos en los \u00f3rganos<\/h4><p class=\"wp-block-paragraph\">Las fibrillas se depositan en los tejidos, en primer lugar en los ri\u00f1ones, y alteran progresivamente su funcionamiento.<\/p><\/div>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-alert aa-tp-alert--wide is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"wp-block-paragraph\">En la amiloidosis AA, la inflamaci\u00f3n suele estar presente desde hace varios a\u00f1os antes de que el amiloide empiece a formarse.<\/p>\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<section class=\"wp-block-group aa-section aa-section--white aa-treating is-layout-flow wp-block-group-is-layout-flow\" id=\"conditions\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group aa-centered-head is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">03<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">Qu\u00e9 mantiene la inflamaci\u00f3n<\/h2>\n\t\t\t<div class=\"aa-divider-dot\"><\/div>\n\t\t\t<p class=\"wp-block-paragraph\">La amiloidosis AA nunca aparece sola. Es consecuencia de otra enfermedad, e identificar cu\u00e1l es el primer paso del tratamiento.<\/p>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-treating-grid is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<div class=\"wp-block-group aa-treating-card is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-icon-tile\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M17 10c.7-.7 1.69 0 2.5 0a2.5 2.5 0 1 0 0-5 .5.5 0 0 1-.5-.5 2.5 2.5 0 1 0-5 0c0 .81.7 1.8 0 2.5l-7 7c-.7.7-1.69 0-2.5 0a2.5 2.5 0 0 0 0 5c.28 0 .5.22.5.5a2.5 2.5 0 1 0 5 0c0-.81-.7-1.8 0-2.5Z\"><\/path><\/svg><\/span><h3 class=\"wp-block-heading\">Artritis inflamatorias<\/h3><p class=\"wp-block-paragraph\">Las enfermedades articulares que mantienen el sistema inmunitario activo durante d\u00e9cadas figuran entre las causas m\u00e1s frecuentes.<\/p><ul class=\"wp-block-list aa-acc__tags\"><li>Artritis reumatoide<\/li><li>Artritis psori\u00e1sica<\/li><li>Espondiloartritis<\/li><li>Gota<\/li><\/ul><\/div>\n\t\t\t<div class=\"wp-block-group aa-treating-card is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-icon-tile\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M2 15c6.667-6 13.333 0 20-6\"><\/path><path d=\"M2 9c6.667 6 13.333 0 20 6\"><\/path><line x1=\"7\" y1=\"6\" x2=\"9\" y2=\"8\"><\/line><line x1=\"15\" y1=\"16\" x2=\"17\" y2=\"18\"><\/line><\/svg><\/span><h3 class=\"wp-block-heading\">Enfermedades autoinflamatorias<\/h3><p class=\"wp-block-paragraph\">Enfermedades gen\u00e9ticas que provocan brotes inflamatorios repetidos, a menudo desde la infancia. Son los pacientes para quienes el cribado es m\u00e1s importante.<\/p><ul class=\"wp-block-list aa-acc__tags\"><li>Fiebre mediterr\u00e1nea familiar<\/li><li>CAPS<\/li><li>MKD<\/li><li>TRAPS<\/li><\/ul><\/div>\n\t\t\t<div class=\"wp-block-group aa-treating-card is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-icon-tile\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M4 3v10a4 4 0 0 0 8 0V7a3 3 0 0 1 6 0v8\"><\/path><circle cx=\"18\" cy=\"18\" r=\"3\"><\/circle><\/svg><\/span><h3 class=\"wp-block-heading\">Enfermedad inflamatoria intestinal<\/h3><p class=\"wp-block-paragraph\">Una inflamaci\u00f3n duradera del tubo digestivo, cuando est\u00e1 mal controlada durante muchos a\u00f1os.<\/p><ul class=\"wp-block-list aa-acc__tags\"><li>Enfermedad de Crohn<\/li><li>Colitis ulcerosa<\/li><\/ul><\/div>\n\t\t\t<div class=\"wp-block-group aa-treating-card is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-icon-tile\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M12 20c-3.3 0-6-2.7-6-6v-3a6 6 0 0 1 12 0v3c0 3.3-2.7 6-6 6z\"><\/path><path d=\"M12 20v-9\"><\/path><path d=\"M6 13H2\"><\/path><path d=\"M22 13h-4\"><\/path><path d=\"m8 2 1.9 1.9\"><\/path><path d=\"M16 2l-1.9 1.9\"><\/path><\/svg><\/span><h3 class=\"wp-block-heading\">Infecciones cr\u00f3nicas<\/h3><p class=\"wp-block-paragraph\">Infecciones que persisten en lugar de curarse, en particular las de los pulmones.<\/p><ul class=\"wp-block-list aa-acc__tags\"><li>Infecciones pulmonares<\/li><\/ul><\/div>\n\t\t\t<div class=\"wp-block-group aa-treating-card is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-icon-tile\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M12 22a7 7 0 0 0 7-7c0-2-1-3.9-3-5.5s-3.5-4-4-6.5c-.5 2.5-2 4.9-4 6.5S5 13 5 15a7 7 0 0 0 7 7z\"><\/path><\/svg><\/span><h3 class=\"wp-block-heading\">Enfermedades de la sangre<\/h3><p class=\"wp-block-paragraph\">Algunas enfermedades hematol\u00f3gicas mantienen un estado inflamatorio a largo plazo.<\/p><ul class=\"wp-block-list aa-acc__tags\"><li>Mieloma<\/li><li>Linfoma no Hodgkin<\/li><li>Enfermedad de Castleman<\/li><\/ul><\/div>\n\t\t\t<div class=\"wp-block-group aa-treating-card is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-icon-tile\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M12 3l2.5 6.5L21 12l-6.5 2.5L12 21l-2.5-6.5L3 12l6.5-2.5z\"><\/path><\/svg><\/span><h3 class=\"wp-block-heading\">Tumores s\u00f3lidos<\/h3><p class=\"wp-block-paragraph\">Una causa m\u00e1s rara, pero reconocida. Algunos tumores mantienen una inflamaci\u00f3n cr\u00f3nica.<\/p><ul class=\"wp-block-list aa-acc__tags\"><li>C\u00e1ncer de pulm\u00f3n<\/li><li>Sarcoma<\/li><li>Carcinoma de c\u00e9lulas renales<\/li><\/ul><\/div>\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<section class=\"wp-block-group aa-section aa-section--cream aa-tp-symptoms is-layout-flow wp-block-group-is-layout-flow\" id=\"symptoms\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group aa-centered-head is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">04<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">S\u00edntomas<\/h2>\n\t\t\t<div class=\"aa-divider-dot\"><\/div>\n\t\t\t<p class=\"wp-block-paragraph\">Los primeros signos son imprecisos y f\u00e1ciles de atribuir a otra cosa. Cuando se hacen evidentes, los ri\u00f1ones suelen estar ya afectados.<\/p>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-organs aa-tp-organs--major is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<div class=\"wp-block-group aa-tp-organ is-layout-flow wp-block-group-is-layout-flow\"><h3 class=\"wp-block-heading\">Ri\u00f1ones<\/h3><p class=\"aa-tp-organ__tag wp-block-paragraph\">La afectaci\u00f3n principal<\/p><p class=\"wp-block-paragraph\">Hinchaz\u00f3n de los tobillos, orina espumosa y un cansancio que el descanso no alivia. Los an\u00e1lisis de sangre muestran que los ri\u00f1ones ya no filtran correctamente. La insuficiencia renal avanzada es la complicaci\u00f3n m\u00e1s grave de la enfermedad y puede llevar a la di\u00e1lisis.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-tp-organ is-layout-flow wp-block-group-is-layout-flow\"><h3 class=\"wp-block-heading\">Tubo digestivo<\/h3><p class=\"aa-tp-organ__tag wp-block-paragraph\">Est\u00f3mago e intestinos<\/p><p class=\"wp-block-paragraph\">La diarrea es la molestia m\u00e1s frecuente. Puede aparecer sangre en las heces. El apetito disminuye y se pierde peso sin haber cambiado voluntariamente de alimentaci\u00f3n.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-tp-organ is-layout-flow wp-block-group-is-layout-flow\"><h3 class=\"wp-block-heading\">H\u00edgado<\/h3><p class=\"aa-tp-organ__tag wp-block-paragraph\">A menudo silenciosa<\/p><p class=\"wp-block-paragraph\">El h\u00edgado aumenta de tama\u00f1o. Curiosamente, las enzimas hep\u00e1ticas suelen permanecer normales, o apenas elevadas, lo que explica en parte que la afectaci\u00f3n pueda pasar inadvertida durante mucho tiempo.<\/p><\/div>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-organs aa-tp-organs--minor is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<div class=\"wp-block-group aa-tp-organ is-layout-flow wp-block-group-is-layout-flow\"><h3 class=\"wp-block-heading\">Tiroides y vejiga<\/h3><p class=\"wp-block-paragraph\">Algunos pacientes desarrollan bocio, un aumento de tama\u00f1o de la tiroides. Cuando la vejiga est\u00e1 afectada, puede aparecer sangre en la orina.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-tp-organ is-layout-flow wp-block-group-is-layout-flow\"><h3 class=\"wp-block-heading\">Coraz\u00f3n<\/h3><p class=\"wp-block-paragraph\">Aqu\u00ed la amiloidosis AA se distingue claramente de la amiloidosis AL. Puede haber dep\u00f3sitos en el coraz\u00f3n, pero los signos de insuficiencia card\u00edaca suelen estar ausentes.<\/p><\/div>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-flags is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-tp-flags__photo is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-doctor-reviewing-medical-imaging-on-a-lightbox-1024x683.jpg\" alt=\"Un m&#xE9;dico examinando im&#xE1;genes m&#xE9;dicas en un negatoscopio\" class=\"wp-image-703\" srcset=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-doctor-reviewing-medical-imaging-on-a-lightbox-1024x683.jpg 1024w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-doctor-reviewing-medical-imaging-on-a-lightbox-300x200.jpg 300w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-doctor-reviewing-medical-imaging-on-a-lightbox-768x512.jpg 768w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-doctor-reviewing-medical-imaging-on-a-lightbox-1536x1024.jpg 1536w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-tp-flags__body is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<h3 class=\"wp-block-heading\">Cu\u00e1ndo consultar<\/h3>\n\t\t\t\t<p class=\"wp-block-paragraph\">Si usted vive con una enfermedad inflamatoria de larga duraci\u00f3n, estos son los signos que conviene comentar con el m\u00e9dico que la sigue.<\/p>\n\t\t\t\t\n\t\t\t\t<ul class=\"wp-block-list aa-tp-flags__list\">\n\t\t\t\t\t<li>Pies y tobillos hinchados<\/li>\n\t\t\t\t\t<li>Orina espumosa<\/li>\n\t\t\t\t\t<li>Cansancio que el descanso no alivia<\/li>\n\t\t\t\t\t<li>Presi\u00f3n arterial baja<\/li>\n\t\t\t\t\t<li>N\u00e1useas y v\u00f3mitos<\/li>\n\t\t\t\t\t<li>Piel seca y con picor<\/li>\n\t\t\t\t\t<li>Calambres musculares<\/li>\n\t\t\t\t\t<li>P\u00e9rdida de apetito<\/li>\n\t\t\t\t\t<li>Diarrea, o sangre en las heces<\/li>\n\t\t\t\t<\/ul>\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t<div class=\"wp-block-group aa-tp-alert is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t\t<p class=\"wp-block-paragraph\">Si se detecta a tiempo, el da\u00f1o renal puede frenarse. Ese es todo el sentido del cribado.<\/p>\n\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<section class=\"wp-block-group aa-section aa-section--white aa-tp-dx is-layout-flow wp-block-group-is-layout-flow\" id=\"diagnosis\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-dx__body is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">05<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">C\u00f3mo se diagnostica la amiloidosis AA<\/h2>\n\t\t\t<p class=\"aa-tp-dx__intro wp-block-paragraph\">Los s\u00edntomas se parecen a los de enfermedades mucho m\u00e1s frecuentes de los ri\u00f1ones, el coraz\u00f3n, los pulmones y el h\u00edgado. Muchos pacientes consultan a varios m\u00e9dicos antes de que por fin se establezca el diagn\u00f3stico, de ah\u00ed la importancia de las etapas siguientes.<\/p>\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-tp-dx__steps is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<div class=\"wp-block-group aa-tp-dx__step is-layout-flow wp-block-group-is-layout-flow\"><p class=\"aa-tp-dx__step-num wp-block-paragraph\">01<\/p><h4 class=\"wp-block-heading\">Confirmar con una biopsia<\/h4><p class=\"wp-block-paragraph\">Solo una biopsia permite tener la certeza. Se examina tejido renal al microscopio en busca de dep\u00f3sitos amiloides.<\/p><\/div>\n\t\t\t\t<div class=\"wp-block-group aa-tp-dx__step is-layout-flow wp-block-group-is-layout-flow\"><p class=\"aa-tp-dx__step-num wp-block-paragraph\">02<\/p><h4 class=\"wp-block-heading\">Tipificar los dep\u00f3sitos<\/h4><p class=\"wp-block-paragraph\">A continuaci\u00f3n se tipifican los dep\u00f3sitos, para establecer que el amiloide est\u00e1 realmente formado por prote\u00edna SAA y no por otro precursor.<\/p><\/div>\n\t\t\t\t<div class=\"wp-block-group aa-tp-dx__step is-layout-flow wp-block-group-is-layout-flow\"><p class=\"aa-tp-dx__step-num wp-block-paragraph\">03<\/p><h4 class=\"wp-block-heading\">Medir la inflamaci\u00f3n<\/h4><p class=\"wp-block-paragraph\">Se miden la SAA circulante y la prote\u00edna C reactiva (PCR). Tambi\u00e9n se revisan los resultados anteriores de PCR: revelan desde hace cu\u00e1nto tiempo dura la inflamaci\u00f3n.<\/p><\/div>\n\t\t\t\t<div class=\"wp-block-group aa-tp-dx__step is-layout-flow wp-block-group-is-layout-flow\"><p class=\"aa-tp-dx__step-num wp-block-paragraph\">04<\/p><h4 class=\"wp-block-heading\">Evaluar los \u00f3rganos<\/h4><p class=\"wp-block-paragraph\">Los an\u00e1lisis de sangre y de orina miden la funci\u00f3n renal, y tambi\u00e9n se examina el coraz\u00f3n. En conjunto, muestran hasta d\u00f3nde han avanzado los dep\u00f3sitos.<\/p><\/div>\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-dx__photo is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-pipette-filling-a-laboratory-sample-vial-1024x683.jpg\" alt=\"Una pipeta llenando un vial de muestra de laboratorio\" class=\"wp-image-704\" srcset=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-pipette-filling-a-laboratory-sample-vial-1024x683.jpg 1024w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-pipette-filling-a-laboratory-sample-vial-300x200.jpg 300w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-pipette-filling-a-laboratory-sample-vial-768x512.jpg 768w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/a-pipette-filling-a-laboratory-sample-vial-1536x1024.jpg 1536w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<section class=\"wp-block-group aa-section aa-section--cream aa-treating is-layout-flow wp-block-group-is-layout-flow\" id=\"treatment\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group aa-centered-head is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">06<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">Tratamiento<\/h2>\n\t\t\t<div class=\"aa-divider-dot\"><\/div>\n\t\t\t<p class=\"wp-block-paragraph\">El tratamiento tiene como objetivo controlar la enfermedad inflamatoria o infecciosa subyacente y reducir la producci\u00f3n de prote\u00edna amiloide A s\u00e9rica (SAA), la prote\u00edna precursora que forma los dep\u00f3sitos amiloides AA.<\/p>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-treat-lead is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-tp-treat-lead__photo is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"745\" src=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/medicine-vials-and-ampoules-1024x745.jpg\" alt=\"Viales y ampollas de medicamentos\" class=\"wp-image-705\" srcset=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/medicine-vials-and-ampoules-1024x745.jpg 1024w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/medicine-vials-and-ampoules-300x218.jpg 300w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/medicine-vials-and-ampoules-768x559.jpg 768w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/medicine-vials-and-ampoules-1536x1117.jpg 1536w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\t\t\t<\/div>\n\t\t\t\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-tp-treat-lead__body is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<h3 class=\"wp-block-heading\">Tratar la causa, no los dep\u00f3sitos<\/h3>\n\t\t\t\t<p class=\"wp-block-paragraph\">El objetivo es reducir el exceso de SAA mal plegada impidiendo que el h\u00edgado la produzca en exceso. Solo hay una manera de lograrlo: controlar la enfermedad inflamatoria subyacente.<\/p>\n\t\t\t\t<p class=\"wp-block-paragraph\">Hay que decirlo claramente: ning\u00fan tratamiento permite hoy eliminar las fibrillas amiloides una vez formadas. Lo que ya se ha depositado permanece. Precisamente por eso, actuar pronto, y hacer el cribado de las personas en riesgo, cambia la evoluci\u00f3n de la enfermedad.<\/p>\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-treating-grid is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<div class=\"wp-block-group aa-treating-card is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-icon-tile\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M10.5 20.5 3.5 13.5a5 5 0 0 1 7-7l7 7a5 5 0 0 1-7 7Z\"><\/path><path d=\"m8.5 8.5 7 7\"><\/path><\/svg><\/span><h3 class=\"wp-block-heading\">Fiebre mediterr\u00e1nea familiar<\/h3><p class=\"wp-block-paragraph\">Un antiinflamatorio diario, tomado de por vida. Suprime los brotes inflamatorios repetidos y, con ellos, el aumento de la SAA.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-treating-card is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-icon-tile\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><path d=\"M12 22s8-4 8-10V5l-8-3-8 3v7c0 6 8 10 8 10z\"><\/path><\/svg><\/span><h3 class=\"wp-block-heading\">Infecciones cr\u00f3nicas<\/h3><p class=\"wp-block-paragraph\">Antibi\u00f3ticos, para eliminar la infecci\u00f3n que manten\u00eda la respuesta inflamatoria.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-treating-card is-layout-flow wp-block-group-is-layout-flow\"><span class=\"aa-icon-tile\"><svg aria-hidden=\"true\" focusable=\"false\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.75\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><circle cx=\"12\" cy=\"12\" r=\"10\"><\/circle><circle cx=\"12\" cy=\"12\" r=\"6\"><\/circle><circle cx=\"12\" cy=\"12\" r=\"2\"><\/circle><\/svg><\/span><h3 class=\"wp-block-heading\">Enfermedad inflamatoria<\/h3><p class=\"wp-block-paragraph\">Corticoides o terapias biol\u00f3gicas, elegidos seg\u00fan la enfermedad y su respuesta al tratamiento.<\/p><\/div>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-support is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<h4 class=\"wp-block-heading\">Cuando los ri\u00f1ones fallan<\/h4>\n\t\t\t<p class=\"wp-block-paragraph\">En caso de insuficiencia renal terminal, el trasplante es posible en pacientes que, por lo dem\u00e1s, gozan de buena salud. Mientras tanto, puede ser necesaria la di\u00e1lisis. Ninguno de los dos elimina el amiloide, pero ambos dan el tiempo que requiere el control de la inflamaci\u00f3n.<\/p>\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<section class=\"wp-block-group aa-section aa-section--forest aa-tp-outlook is-layout-flow wp-block-group-is-layout-flow\" id=\"follow-up\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-outlook__photo is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/two-people-holding-hands-1024x683.jpg\" alt=\"Dos personas tomadas de la mano\" class=\"wp-image-706\" srcset=\"https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/two-people-holding-hands-1024x683.jpg 1024w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/two-people-holding-hands-300x200.jpg 300w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/two-people-holding-hands-768x512.jpg 768w, https:\/\/www.amyloidosisalliance.org\/wp-content\/uploads\/2026\/09\/two-people-holding-hands-1536x1024.jpg 1536w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-outlook__body is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">07<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">Prevenci\u00f3n y seguimiento<\/h2>\n\t\t\t<h4 class=\"wp-block-heading\">Cribado<\/h4>\n\t\t\t<p class=\"wp-block-paragraph\">La prevenci\u00f3n es especialmente importante para las personas que viven desde la infancia con una enfermedad autoinflamatoria gen\u00e9tica. Necesitan un tratamiento antiinflamatorio de por vida y un control una vez al a\u00f1o para detectar una amiloidosis antes de que haya causado da\u00f1os.<\/p>\n\t\t\t\n\t\t\t<div class=\"wp-block-group aa-aa-screening is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t<p class=\"aa-aa-screening__label wp-block-paragraph\">Una vez al a\u00f1o<\/p>\n\t\t\t\t\n\t\t\t\t<div class=\"wp-block-group aa-aa-screening__items is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\t\t<p class=\"aa-aa-screening__item wp-block-paragraph\">Un an\u00e1lisis de orina, para detectar una p\u00e9rdida de prote\u00ednas por los ri\u00f1ones<\/p>\n\t\t\t\t\t<p class=\"aa-aa-screening__item wp-block-paragraph\">Un an\u00e1lisis de sangre, para medir la inflamaci\u00f3n y la funci\u00f3n renal<\/p>\n\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t\t<h4 class=\"wp-block-heading\">Un seguimiento compartido<\/h4>\n\t\t\t<p class=\"wp-block-paragraph\">Una vez confirmada la amiloidosis AA, el seguimiento es estrecho e implica a varios profesionales a la vez: el m\u00e9dico que trata la enfermedad inflamatoria subyacente, su m\u00e9dico de cabecera y un especialista en amiloidosis AA. Cada uno ve una parte distinta del cuadro.<\/p>\n\t\t\t<p class=\"aa-tp-outlook__closing wp-block-paragraph\">Algunos casos de amiloidosis AA pueden prevenirse mediante un control precoz y sostenido de la enfermedad inflamatoria o infecciosa subyacente. Eso es lo que hace que el control anual valga la pena.<\/p>\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<section class=\"wp-block-group aa-section aa-section--white aa-tp-faq is-layout-flow wp-block-group-is-layout-flow\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group aa-centered-head is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">FAQ<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">Preguntas frecuentes<\/h2>\n\t\t\t<div class=\"aa-divider-dot\"><\/div>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-acc is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t\n\t\t\t<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>\u00bfLa amiloidosis AA es hereditaria?<\/summary>\n\t\t\t<p class=\"wp-block-paragraph\">La amiloidosis AA en s\u00ed no es hereditaria, pero algunas de las enfermedades que la provocan s\u00ed lo son. La fiebre mediterr\u00e1nea familiar, el CAPS, el MKD y el TRAPS son enfermedades autoinflamatorias gen\u00e9ticas que pueden transmitirse en las familias. Si se ha diagnosticado una de ellas en su familia, pregunte a su m\u00e9dico si sus familiares deber\u00edan ser evaluados.<\/p>\n\t\t\t<\/details>\n\t\t\t\n\t\t\t\n\t\t\t<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>\u00bfSe puede prevenir la amiloidosis AA?<\/summary>\n\t\t\t<p class=\"wp-block-paragraph\">En gran medida, s\u00ed, y esto distingue a la amiloidosis AA de las dem\u00e1s formas. Mantener controlada la inflamaci\u00f3n subyacente mantiene bajos los niveles de SAA, y sin exceso de SAA no hay materia prima para el amiloide. Para las personas con una enfermedad autoinflamatoria gen\u00e9tica, la prevenci\u00f3n, en la pr\u00e1ctica, consiste en un tratamiento de por vida y un control anual.<\/p>\n\t\t\t<\/details>\n\t\t\t\n\t\t\t\n\t\t\t<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>\u00bfEl tratamiento elimina los dep\u00f3sitos?<\/summary>\n\t\t\t<p class=\"wp-block-paragraph\">No. Ning\u00fan tratamiento disponible actualmente elimina las fibrillas amiloides ya formadas. El tratamiento impide que se formen otras nuevas, lo que permite que los \u00f3rganos se estabilicen y, en algunos casos, recuperen parte de su funci\u00f3n. Lo que ya se ha depositado permanece.<\/p>\n\t\t\t<\/details>\n\t\t\t\n\t\t\t\n\t\t\t<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>\u00bfLa amiloidosis AA afecta al coraz\u00f3n?<\/summary>\n\t\t\t<p class=\"wp-block-paragraph\">Puede haber dep\u00f3sitos en el coraz\u00f3n pero, a diferencia de la amiloidosis AL, los signos de insuficiencia card\u00edaca suelen estar ausentes. En la amiloidosis AA, son los ri\u00f1ones, y no el coraz\u00f3n, los que dominan el cuadro cl\u00ednico.<\/p>\n\t\t\t<\/details>\n\t\t\t\n\t\t\t\n\t\t\t<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>\u00bfQu\u00e9 es la SAA?<\/summary>\n\t\t\t<p class=\"wp-block-paragraph\">La prote\u00edna amiloide A s\u00e9rica es una prote\u00edna fabricada por el h\u00edgado. Circula en la sangre en concentraciones bajas, y su producci\u00f3n aumenta como parte de la respuesta normal del organismo a la inflamaci\u00f3n. En la amiloidosis AA, una inflamaci\u00f3n que nunca se apaga mantiene la SAA elevada durante a\u00f1os, hasta que una parte se pliega mal y forma dep\u00f3sitos.<\/p>\n\t\t\t<\/details>\n\t\t\t\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-tp-disclaimer is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"wp-block-paragraph\">Esta p\u00e1gina ofrece informaci\u00f3n general destinada a pacientes, familias y profesionales sanitarios. No sustituye al consejo m\u00e9dico. Hable siempre de su situaci\u00f3n con su equipo especializado.<\/p>\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n\n<section class=\"wp-block-group aa-next aa-next--split is-layout-flow wp-block-group-is-layout-flow\">\n\t\n\t<div class=\"wp-block-group aa-inner is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\n\t\t<div class=\"wp-block-group aa-next__head is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<p class=\"aa-section-num wp-block-paragraph\">Continuar<\/p>\n\t\t\t<h2 class=\"wp-block-heading\">Otros tipos<\/h2>\n\t\t<\/div>\n\t\t\n\t\t\n\t\t<div class=\"wp-block-group aa-next__grid is-layout-flow wp-block-group-is-layout-flow\">\n\t\t\t<div class=\"wp-block-group aa-next-card is-layout-flow wp-block-group-is-layout-flow\"><h3 class=\"wp-block-heading\"><a href=\"https:\/\/www.amyloidosisalliance.org\/types-of-amyloidosis\/al-amyloidosis\/\">Amiloidosis AL<\/a><\/h3><p class=\"wp-block-paragraph\">La forma sist\u00e9mica m\u00e1s frecuente, causada por cadenas ligeras producidas en la m\u00e9dula \u00f3sea.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-next-card is-layout-flow wp-block-group-is-layout-flow\"><h3 class=\"wp-block-heading\"><a href=\"https:\/\/www.amyloidosisalliance.org\/types-of-amyloidosis\/attr-amyloidosis\/\">Amiloidosis ATTR<\/a><\/h3><p class=\"wp-block-paragraph\">Causada por la transtiretina, hereditaria en la ATTRv, asociada a la edad en la ATTRwt.<\/p><\/div>\n\t\t\t<div class=\"wp-block-group aa-next-card is-layout-flow wp-block-group-is-layout-flow\"><h3 class=\"wp-block-heading\"><a href=\"https:\/\/www.amyloidosisalliance.org\/es\/otros-tipos\/\">Otros tipos<\/a><\/h3><p class=\"wp-block-paragraph\">Las formas hereditarias raras, y la amiloidosis localizada, limitada a un solo sitio.<\/p><\/div>\n\t\t<\/div>\n\t\t\n\t<\/div>\n\t\n<\/section>\n","protected":false},"excerpt":{"rendered":"<p>Inicio\u203aAmiloidosis\u203aTipos de amiloidosis\u203aAmiloidosis AA Tipos de amiloidosis Amiloidosis AA La amiloidosis AA es una complicaci\u00f3n de una inflamaci\u00f3n de larga duraci\u00f3n. No es hereditaria ni es un c\u00e1ncer de la sangre: se desarrolla cuando otra enfermedad mantiene el organismo inflamado durante a\u00f1os. Controlar esa enfermedad es lo que la detiene, lo que convierte a la [&hellip;]<\/p>\n","protected":false},"author":0,"featured_media":0,"parent":2475,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-2469","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Amiloidosis AA: causas, s\u00edntomas y tratamiento<\/title>\n<meta name=\"description\" content=\"La amiloidosis AA aparece tras a\u00f1os de inflamaci\u00f3n no tratada. 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