{"id":4078,"date":"2023-01-26T08:37:00","date_gmt":"2023-01-26T07:37:00","guid":{"rendered":"https:\/\/www.amyloidosisalliance.org\/neue-fap-ausloesende-mutation-bei-aelterem-mann-in-deutschland-entdeckt\/"},"modified":"2026-11-03T10:19:04","modified_gmt":"2026-11-03T09:19:04","slug":"neue-fap-ausloesende-mutation-bei-aelterem-mann-in-deutschland-entdeckt","status":"publish","type":"post","link":"https:\/\/www.amyloidosisalliance.org\/de\/neue-fap-ausloesende-mutation-bei-aelterem-mann-in-deutschland-entdeckt\/","title":{"rendered":"Neue FAP-ausl\u00f6sende Mutation bei \u00e4lterem Mann in Deutschland entdeckt"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Neue FAP-ausl\u00f6sende Mutation bei \u00e4lterem Mann in Deutschland entdeckt <\/p>\n\n<p class=\"wp-block-paragraph\">Der Fall unterstreicht die Notwendigkeit von Genanalyse und Anamnese bei der ATTR-Amyloidose, so die Forschenden <\/p>\n\n<p class=\"wp-block-paragraph\">\u201eBei einem \u00e4lteren Mann in Deutschland wurde eine Kopie einer neuen Mutation im TTR-Gen festgestellt, die sowohl neurologische als auch kardiale Symptome einer famili\u00e4ren Amyloid-Polyneuropathie (FAP) verursachte; diese wurden in einem aktuellen Fallbericht beschrieben.<\/p>\n\n<p class=\"wp-block-paragraph\">Der Fall des Mannes erfordere \u201eeine sorgf\u00e4ltige molekulargenetische Analyse und Anamnese bei jedem Fall von ATTR-Amyloidose \u2026, um seltene F\u00e4lle heredit\u00e4rer ATTR-Amyloidose nicht zu \u00fcbersehen und geeignete krankheitsmodifizierende Behandlungen anzubieten\u201c, so die Forschenden.\u201c<\/p>\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/fapnewstoday.com\/news\/new-fap-causing-gene-mutation-found-elderly-man-germany\/?utm_source=FAP&amp;utm_campaign=bea407cb5b-FAP_ENL_3.0_NON_US&amp;utm_medium=email&amp;utm_term=0_be787937ec-bea407cb5b-74444834&amp;fbclid=IwAR1_GF7DdRI0YQvxeU33ayg-5LBu-zpqS7gjABsLWE1GUegiyYZLXTBt0-s\">Mehr dazu hier<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ein Fallbericht beschreibt eine neue Variante des TTR-Gens bei einem \u00e4lteren Mann in Deutschland, eine Erinnerung daran, wie wichtig sorgf\u00e4ltige Gentests bei der ATTR-Amyloidose sind.<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[40],"tags":[],"class_list":["post-4078","post","type-post","status-publish","format-standard","hentry","category-uncategorized-de"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Neue FAP-ausl\u00f6sende Mutation bei \u00e4lterem Mann in Deutschland entdeckt<\/title>\n<meta name=\"description\" content=\"Ein Fallbericht beschreibt eine neue Variante des TTR-Gens bei einem \u00e4lteren Mann in Deutschland, eine Erinnerung daran, wie wichtig sorgf\u00e4ltige 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